ISOLUTE® PPT+ Protein Precipitation Plates

Unlike membrane based devices, the system has an optimized porosity distribution and acts as a depth filter, holding up the precipitated protein without well blockage.

Using the ‘solvent first’ methodology, ISOLUTE® PPT+ plates consistently produce clear filtrates. This reduces ion suppression and improves the accuracy of LC-MS/MS analysis compared to alternative protein precipitation procedures. Up to 96 samples containing acidic, basic or neutral drug compounds can be purified simultaneously in less than ten minutes.

ISOLUTE PPT+ is available in fixed well 96-well plate format. Process manually using the VacMaster™-96 Sample Processing Manifold or Biotage® PRESSURE+ 96 Positive Pressure Manifold. The simple procedure can be fully automated using Biotage® Extrahera or other  96-well liquid handling systems.