The Biotage® Flash 400 system is a complete skid-mounted system designed for kilogram scale separations. Built to last and engineered to perform, with materials that comply with FDA regulations and cGMP standards, Flash 400 is the first choice of pharmaceutical and contract manufacturing companies around the world for critical purification applications.
Purify up to 400 grams of compound at 1L/min up to 75% faster than with traditional glass columns. Biotage® Flash 75/150 is a simple and reliable system that contains everything you need for separation scale up.
Sfär is the Swedish word for "sphere", and the name of our columns reflects the fact that we have made spherical silica a standard due to its higher surface area and higher loading capacity. Reliable and flexible, Biotage® Sfär columns deliver larger loading capacities, tighter elution bands and purer fractions than traditional flash columns.
Reversed-phase flash chromatography is a very effective purification technique. Its main application areas include polar, ionizable and highly lipophilic compounds which cannot easily be separated by normal-phase techniques.
Biotage® KP-NH chemistry shields synthetic organic amines from acidic silanols providing improved selectivity, peak shape, purity and yield. Unlike traditional silica and 1° amine (propyl amine) bonded silica, Biotage KP-NH doesn’t require the use of chlorinated solvents or amine additives.
Biotage SNAP Ultra flash chromatography cartridges deliver the highest purification performance available. Packed with Biotage® HP-Sphere™ spherical silica, these cartridges have the highest loading capacity, lowest backpressure and can withstand high flow rates.
Biotage® SNAP are designed with the ability to dry load a sample within the cartridge. Sometimes, the amount of adsorbent required exceeds the cartridge’s dry load capacity, or in the case of some formats, the dry loading needs to be external. When that situation arises, the Biotage DLV systems provide a convenient in-line solution.
Isolera™ Dalton is the most advanced and innovative flash purification system available, designed by people who understand flash chromatography for the chemists who need it. "Pure convenience! Just pure convenience! It lets us perform purification and analysis at the same time. It gives us tremendous power to isolate unknown compounds.” - Hiroki Nishii, Chugai Pharmaceutical’s Kamakura Research Laboratories
Isolera™ Prime is a value based system which recommends appropriate cartridges and calculates the best solvent conditions and gradients for your purifications. It has solvent pumps, automated fraction collection as standard and delivers much more than just the basics. Solvent use is minimized and advanced compound detection makes sure that your purified compound is delivered at the end of the run. We belive in providing value, so Isolera Prime systems embrace ACI™, a revolutionary advancement, converting regular flash from simple purification to the fastest, greenest, and most economical way to reliably isolate pure compounds for organic synthesis. ACI offerred as standard on Isolera Prime.
Isolera™ Spektra is a high performance ACI™ Accelerated Chromatographic Isolation system. Available as Isolera Spektra One, Four and LS, with time, efficiency and cost saving purification run features that are normally only found on the world’s most expensive high-end chromatography systems. With Isolera™ Assist you get the benefits of the feature-rich Isolera Flash Purification Systems in a simple and easy to use interface. It ensures you achieve the best results, regardless of your experience level.
Phase separators are a range of columns fitted with a selectively permeable, optimized frit material that separates aqueous phase from an organic phase under gravity. The design is as simple as it is ingenious. There are no moving parts and nothing to prime, it’s all achieved by hydrophobic/hydrophilic interactions.
Load samples onto the column more effectively than with traditional liquid loading. Designed exclusively to complement the SNAP cartridge format, Samplets allow you to boost flash purification performance without changing your purification strategy.