Biotage ZIP® flash cartridges are an evolution in Biotage’s long history of manufacturing flash purification solutions. Biotage ZIP cartridges deliver industry-leading performance that meet the difficult challenges of day to day purification.
Biotage ZIP® Sphere delivers better purification and improved throughput than comparable flash cartridges. The silica surface area has been increased by 40%, meaning higher loading capacity, improved separations, and reduced purification time and solvent use.
Biotage® ELSD (evaporative light-scattering detector) is a universal detector designed for use with Isolera™ flash purification systems when purifying organic compounds that are undetectable UV or visible light.
The Endeavor Catalyst Screening System is a parallel, multi-reactor synthesizer for fast, effective and simple optimization of pressurized reactions. Parallel reactors and automated control of pressurization, heating and mixing provides rapid assessment of reaction conditions to dramatically increase productivity.
The Biotage® Flash 400 system is a complete skid-mounted system designed for kilogram scale separations. Built to last and engineered to perform, with materials that comply with FDA regulations and cGMP standards, Flash 400 is the first choice of pharmaceutical and contract manufacturing companies around the world for critical purification applications.
Fast Scale-up: Gram To Multi-Gram Quantities Of Target Organic Compounds
Purify up to 400 grams of compound at 1L/min up to 75% faster than with traditional glass columns. Biotage® Flash 75/150 is a simple and reliable system that contains everything you need for separation scale up.
Rapidly synthesize high quality peptides using microwave irradiation. A cost effective and versatile accessory for manual microwave peptide synthesis and cleavage when used with a Biotage® Initiator+ microwave synthesizer.
Biotage® Initiator+ represents the latest in microwave synthesis performance. This instrument’s high-end specifications enable the chemist to explore new areas and perform the latest of innovations in chemistry. A reliable and upgradeable platform that allows chemists to make great discoveries in less time.
Biotage® Initiator+ Alstra™ is a fully automated microwave peptide synthesizer . With functionality such as Branches, Preactivation and “Edit on the fly”, and options for UV monitoring and MAOS (organic synthesis) capability, this instrument represents best-in-class systems for both small and large scale synthesis of peptides, peptoids, PNA and peptidomimetics.
“The Initiator+ SP Wave – I think it’s an amazing little beast. Semi-automated, which I think is ideal for an academic lab making lots of bizarre peptides and exotics on a day-to-day basis then it’s a fantastic instrument. You can make PNA and ours has worked amazingly well in terms of the purity of materials obtained”
Prof Mark Bradley, School of Chemistry, University of Edinburgh
Automation for Microwave Assisted Organic Synthesis
Biotage® Initiator+ can be upgraded from a single-sample manual format to an automated 8- or 60-position system. The modular design allows a user to add on different automated sample processors dependent on throughput requirements.
Sfär is the Swedish word for "sphere", and the name of our columns reflects the fact that we have made spherical silica a standard due to its higher surface area and higher loading capacity. Reliable and flexible, Biotage® Sfär columns deliver larger loading capacities, tighter elution bands and purer fractions than traditional flash columns.
Biotage® SNAP Bio flash cartridges were developed with a small particle size (20 μm) and large pore size (300 Å) to provide increased resolution and the effective separation of complex peptide mixtures.
Reversed-phase flash chromatography is a very effective purification technique. Its main application areas include polar, ionizable and highly lipophilic compounds which cannot easily be separated by normal-phase techniques.
Biotage® KP-NH chemistry shields synthetic organic amines from acidic silanols providing improved selectivity, peak shape, purity and yield. Unlike traditional silica and 1° amine (propyl amine) bonded silica, Biotage KP-NH doesn’t require the use of chlorinated solvents or amine additives.