PFAS Sample Prep Workflow

The detection of per- and polyfluoroalkyl substances (PFAS) within our air, water, and soil has confirmed their place as persistent pollutants that pose significant health risks upon human exposure, including metabolic changes, elevated cholesterol levels, and increased cancer risks.

As governments are spurred to take action and monitor the levels of these compounds, Biotage understands the need for simple and robust sample preparation procedures and has a number of solutions tailored to environmental and biological fluid matrices.

Homogenization

The concentration of PFAS analytes can be higher in certain portions of solid samples, therefore sample homogenization is key in screening solid matrices for toxic substances.

Biotage® Lysera

The Lysera is specifically designed for automating the grinding, lysing, and homogenizing of biological samples.

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Processing

Biotage® Extrahera™

The Biotage® Extrahera™ family consists of three automated sample preparation workstations; the Extrahera™ LV-200 dedicated to 96-well plate processing, the Extrahera™ HV-5000 for 3-, 6-, 10- and 15-mL column-based sample prep, and the Extrahera™ Classic that can process both plate and column formats.

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Biotage® VacMaster™

Biotage® VacMaster™ Sample Processing Manifolds allow up to 10 or 20 SPE or filtration columns to be processed simultaneously under vacuum. Easy to use vacuum controls provide excellent sample flow control, leading to reproducible, reliable extraction conditions.

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Biotage® PRESSURE+

The Biotage® PRESSURE+ system utilizes a consistent, uniform flow of positive pressure to move both low and high viscosity liquids through SPE columns. Each port independently maintains constant pressure, increasing the overall reproducibility of analyte recoveries.

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Consumables

There are multiple sample preparation methods used as a basis for PFAS testing around the world, depending on local regulations, matrix and the specific laboratory's needs. Explore our consumable solutions for PFAS extraction, in compliance with the top methodologies.

Matrix