Mycophenolic acid is an active metabolite produced by the hydrolysis of the immunosuppressive agent mycophenolate mofetil in the body. It is considered important to control pharmacokinetic parameters such as AUC (area under the blood concentration-time curve) and trough concentration in order to prevent acute rejection after organ transplantation.
In this application note, ISOLUTE® SLE+ was used as a sample pretreatment column for mycophenolic acid determination in plasma using the principles of supported liquid extraction (SLE).
Mycophenolic acid (Mycophenolic acid, CAS: 137234-62-9)
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