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Method Development Suite - A Seminar by Biotage

19 April 2019

A Simplified Approach to Developing Better Sample Prep Methods for Clinical Labs

A Hands-On, Full Day Seminar by Biotage Chemists

  • April 19, 2019: Courtyard San Francisco Airport/Oyster Point Waterfront 1300 Veterans Blvd, South San Francisco, CA 94080
  • May 16, 2019: Courtyard by Marriott Princeton 3815 US Route 1 @ Mapleton Road Princeton, NJ 08540

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The Biotage Method Development Suite is a 5 part training course for clinical labs, and offers a proven, systematic approach to sample preparation method development for chromatography mass spectrometry assays.  The objective is to provide the research scientist with the knowledge and tools to develop sample preparation methods based on specimen type and compounds of interest with a minimal number of experiments.

This hotel version includes a hands-on introduction to some options for processing and automation of the method once developed and the training includes processing points that should be considered at the time of method development.

SlidesSummary of the Method Development Suite

  • Part 1:  Introduction of the system utilizing the suite of plates
  • Part 2:  Systematic development for Blood
  • Part 3:  Systematic development for Urine
  • Part 4:  Systematic method development for Alternate Matrices
  • Part 5:  Considerations for Automation and Processing Samples


  • 9:00 – 10:30  Part 1
  • 10:45 – 11:15  Part 2
  • 11:30 – 12:00  Part 3
  • 12:00 Lunch
  • 1:00 – 1:45  Part 4
  • 2:00 – 3:00  Part 5 with hands on the systems (Attendees can stay longer if desired)

*Times subject to change. 


Mohamed Youssef, MBA

Mohamad YoussefSenior Applications Chemist, Biotage

Mohamed Youssef is currently Sr. Applications Chemist for Biotage where he applies his 18 years of experience to develop and present novel GC, GC/MS, HPLC, LC/MS/MS and SPE/MS/MS application directed toward clinical, forensic, and biopharmaceutical industries using a variety of sample prep techniques.

Youssef previously served as Technical and R&D Director for Amerispec Diagnostics FZ-LLC – the first ISO accredited reference clinical laboratory using Mass Spectrometry in the UAE and in the Middle East – where he was responsible for overseeing all testing activities in the laboratory to ensure rapid economical and efficient turnaround of high quality test analyses. Previous to that, he was Regional Sales and Support Manager for the Northeast for MedTest DX., also as a Manufacturer’s Representative (New England Clinical Account Manager) for Agilent Technologies. Prior to that, Mr. Youssef served as an Applications Scientist for Agilent Technologies. Prior to Agilent Technologies, Mohamed was a Clinical Applications Specialist at UMass Memorial Medical Center. In this role he was responsible for developing methods using Mass Spectrometry, Chromatography instruments, and providing clinical scientific education.

Mohamed held various positions in reference clinical laboratories such as Quest Diagnostics and Mayo Medical Laboratories, concentrating on Toxicology and Therapeutic Drug Monitoring.

Stephanie J. Marin, Ph.D.

Stephanie MarinSenior Applications Chemist. Biotage

Stephanie J. Marin received her Ph.D. in chemistry from Arizona State University. She has expertise in sample preparation, liquid chromatography, and mass spectrometry, and has gained over 10 years of experience developing and validating clinical assays from her tenure at the ARUP Institute for Clinical and Experimental Pathology.  She has additional experience doing analytical work on polymers, adhesives, coatings, food packaging, and other specialty chemicals. Stephanie has worked in applications development and marketing for an HPLC instrument and column manufacturer, and as a supervisor at an EPA certified lab. She is the author of over 30 peer reviewed publications and book chapters and over 80 abstracts presented at national meetings.


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