Biotage® Metal Scavenging Screening Kits

Biotage metal scavengers are available in loose powder form, which can be added and stirred into batch reactions. Alternatively they can be packed into column formats for flow through applications.

Key supplier to industry for over 20 years, used in numerous patents and cGMP process campaigns

From grams in research through to multi kilogram quantities in production campaigns

Lot control, QA / QC documentation, SDS, ISO 9001 / 14001 registration, BSE / TSE statement, shelf-life statement

K-MS-2 – Loose Powder Based Kit

• 1 x 10 g Si Thiol
• 1 x 3 g ISOLUTE® Si-TMT
• 1 x 3 g Biotage® MP-TMT
• 1 x 10 g ISOLUTE® SCX-2
• 1 x 10 g ISOLUTE® Si-Trisamine
• 5 x 500 mg/6 mL ISOLUTE® Si-TMT (1 sampler pack)

K-MS-3 – Pre-packed SPE Cartridges Kit

• 5 x 1g/15mL SPE cartridge Biotage® MP-TMT
• 5 x 1g/15mL SPE cartridge ISOLUTE® Si-TMT
• 5 x 1g/15mL SPE cartridge ISOLUTE® Si-Thiol
• 5 x 1g/15mL SPE cartridge ISOLUTE® Si-Trisamine
• 5 x 1g/15mL SPE cartridge ISOLUTE® SCX-2

• Incorporating the industry leading universal metal scavenger, Biotage® MP-TMT
• Higher metal affinity – low Kd(Pd) relative to API Kd(Pd) – excellent metal scavenging
• Fast kinetics / filtration at room temperature – enhanced by heating
• Diverse solid supports – silica and polystyrene backbones
• Work Flow Compatible – generic, use in diverse conditions
• Minimal loss of API – less / no non-specific binding
• Higher purity of final product – no leachables
• Short development time – faster method optimization
• Shelf-Life and Stability
• Mechanically robust, and may be stirred vigorously without breakdown
• Bioanalytical grade silica
• Can be added in batch processes and stirred
• Optimum flow characteristics as fixed beds
• May be stored in closed containers at RT, or longer term in a cool dry (4 °C) environment.