This method describes the clean-up of acrylamide from cooked foodstuffs, using a multimode retention mechanism (hydrophobic, cation and anion exchange) for retention of interfering food components. The analytical technique is LC-MS-MS. ISOLUTE, MULTIMODE, SPE, FOOD, FOOD SCARE

Acrylamide Application Notes Column Food Food Food contaminant LC-MS/MS

This application note was developed for the clean-up of a non-polar solvent extract of vegetable material. The methodology is applicable to a wide range of organochlorine and organophosphorus pesticides and a number of vegetable types. The analytes are relatively non-polar, and will not be strongly retained by polar/anion exchange sorbents.

Application Notes Clordane Column Dicofol Endosulfan Food Food GC-MS Organochlorines Organophosphate Pesticide Organophosphates Pesticides Vegetables

This method was developed for the extraction of the tetrahydrocannabinol carboxylic acid metabolite (THC-COOH) from urine using a mixed non-polar and anion exchange retention mechanism. Typical recoveries of the analyte are > 75%. THC, THC-COOH, BIOTAGE, ISOLUTE, SPE, DOA, drugs of abuse

Application Notes Column Forensic GC-MS THC-COOH Urine

Biotage® PRESSURE+ manifolds deliver positive pressure, parallel processing for 96 well plates and column formats. The systems utilize a consistent, uniform flow of positive pressure to move both low and high viscosity liquids through SPE plates and columns. ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation and greatly matrix effects associated with biofluid analysis. SLE+, SLE, Supported Liquid Extraction, positive pressure manifold, Pressure+96, Pressure+48

Application Notes Aqueous Biological fluids Column Plasma Post-Mortem fluids Urine Water Whole blood

This method is applicable to the determination of Oil and Grease as defined by EPA Method 1664 as Hexane Extractable Material (HEM, also referred to as Total Oil and Grease) as well as Silica Gel Treated-Hexane Extractable Material (SGT-HEM, also referred to as Total Petroleum Hydrocarbons or TPH). EPA, Fractionation, EPA Method 1664, TPH, Total Petroleum Hydrocarbons

Application Notes Column Environmental Hexane Extractable Material Oil & Grease Water

The use of ISOLUTE HCX mixed-mode sorbents is widely accepted for providing high purity extracts of basic drugs from biological fluids. The ISOLUTE HCX-Q sorbent utilizes a combination of weak cation exchange and C8 non-polar retention mechanisms.

Product Notes

This technical note includes a general discussion on non-polar sorbents , specifics on the use of ISOLUTE ENV+ for the extraction of polar analytes from aqueous samples), and ordering information.

Application Notes Product Notes

The ISOLUTE HCX series of mixed-mode SPE sorbents is based on a combination of strong cation exchange and non-polar chemistries. Basic drugs are retained by two primary retention mechanisms. This allows a rigorous interference elution regime to be used to elute interferences retained by either non-polar or cation exchange interactions alone. Only analytes with both non-polar and basic characteristics are extracted using the ISOLUTE HCX series of sorbents, providing an extremely pure final extract.

Product Notes

ISOLUTE HAX mixed-mode SPE sorbent is based on a combination of strong anion exchange and non-polar chemistries. Acidic drugs are retained by two primary retention mechanisms. This allows a rigorous interference elution regime to be used to elute interferences retained by either non-polar or anion exchange interactions alone. Only analytes with both non-polar and acidic characteristics are extracted usign the ISOLUTE HAX sorbent, providing an extremely pure final extract.

Product Notes

This Chemistry Data Sheet includes specifics on the use of ISOLUTE 101 for the extraction of polar analytes from aqueous samples, ordering information and a general discussion on non-polar sorbents.

Product Notes

This technical note details the use of ISOLUTE® HM-N, a diatomaceous earth material, for use in rapid sample preparation by supported liquid extraction.

Product Notes

ISOLUTE® HCX columns are based on cation exchange and C8 mixed mode chemistries. Basic drugs are therefore retained by two primary retention mechanisms - ionic and non-polar. This allows a more rigorous interference elution regime to be used, leading to a very clean final extract, as many non-polar interferences which are retained by a non-polar interaction alone, can be eluted selectively, prior to elution of the drug.

Application Notes English

Speeding up reactions has never been easier. Biotage microwave synthesizers are the first-choice tools for organic chemists who need to accelerate their production of new compounds. Initiator, Initiator+, robot, vials, phase separator, work up tools

Brochures

ISOLUTE® SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquidliquid extraction (LLE) for bioanalytical sample preparation, extracting up to 10 mL of aqueous sample. ISOLUTE SLE+ provides high analyte recoveries, eliminates emulsion formation and reduces sample preparation time by half.

Product Notes

Biotage® PRESSURE+ manifolds deliver positive pressure, parallel processing for 96 well plates, 1 mL 3 mL and 6 mL column formats. The systems utilize a consistent, uniform flow of positive pressure to move both low and high viscosity liquids through SPE plates and columns. Each port of the PRESSURE+ manifold independently maintains constant pressure, increasing the overall reproducibility of analyte recoveries. This unique design allows for partially populated racks to be used without sacrificing extraction efficiency.

Product Notes

This application note describes the extraction and clean-up of mineral oil (petroleum oil) from water samples according to ISO 9377-2:2000. This method involves a liquid-liquid extraction step followed by clean up using an SPE column containing layers of sodium sulfate and florisil, to remove halogenated and other polar interferences from the extract.

Application Notes

Laboratory chemical Not for therapeutic or diagnostic use

English Material Safety Data Sheets

Laboratory chemical Not for therapeutic or diagnostic use

English Material Safety Data Sheets

Initiate success in Chemical education with Microwave Assisted Organic Synthesis. This leaflet contain example reactions that could be adapted for use in the teaching laboratory. Keywords: initiator+

English Manuals & User Guides Pharma

This Chemistry Data Sheet provides procedures for both the automated and manual fractionation of EPH in soil. The automated procedure is described on page 2 and the manual procedure is outlined on page 3. Chromatograms illustrate the ability of ISOLUTE EPH to provide efficient fractionation of hexane or pentane soil extracts into aliphatic and aromatic fractions (see Appendix).

Product Notes Soil