In this application note, a suite of neutral and list 1 pesticides in methylene chloride is evaporated using the Biotage® DryVap. Pesticides containing many different functional groups, including sulfur and phosphorus groups, halides, nitramines, atrazines, alcohol, and carbonyl groups were efficiently concentrated for GCMS analysis. This data indicates that the DryVap System is inert and effectively manages solvent evaporation without generating localized hot spots in the system.

Application Notes English Environmental GC-MS Organochlorine pesticides (OCP) Organophosphate Pesticide Pesticides Water

EPA Method 1657 describes the procedure to determine low ppb levels of organophosphorous pesticides in wastewater. The disks compared in this study are: “Certified for Automation” Atlantic™ C18 (47 mm) and 3M Empore™ High Performance Extraction Disk C18 (47 mm).

4790 Application Notes Azinphos methyl Chlorpyrifos Demeton (O&S) Diazinon Disk Disulfoton EPA 1657 analytes EPN English Environmental Ethion Ethyl parathion GC-FPD Malathion Methyl parathion Organophosphate Pesticide Waste water

This paper demonstrates how the introduction of simple automated technology and a modification in analysis. Can positively impact analytical results and overall throughput for critical environmental testing.

Application Notes Environmental GC-MS Organophosphate Pesticide

This application note was developed to demonstrate the extraction of five organophosphate compounds Monocrotophos, Diazinon, Malathion, EPN, and Methamidophos using one solid phase extraction method with one pre-treatment step of sodium chloride (NaCl). The method uses the Biotage® Horizon 4790 automated SPE extraction system. It will show the efficiency of the extraction while demonstrating excellent recoveries of OPP compounds using methylene chloride and minimal amounts of acetone after sample pre-treatment with sodium chloride. Methods were developed and results are shown using 47 mm Atlantic® HLB-H disks and carbon cartridges.

4790 Application Notes Diazinon Disk EPN English Environmental GC-MS Malathion Methamidophos Monocrotophos Organophosphate Pesticide US EPA Method 608.3 Water

Method 1657 describes the procedure to determine low ppb levels of organophosphorus pesticides in municipal and industrial wastewater. The City of Fort Worth Water Department implemented Automated SPE for the analysis of organophosphorous pesticides by EPA Method 1657, using the Atlantic™ C18 solid phase extraction disk. The Biotage® Horizon 4790 Automated Extraction System with Envision® Platform controller, and the DryVap® Automated Drying and Concentration System were used in this application note.

4790 Application Notes Azinphos methyl Chlorpyrifos Demeton (O&S) Diazinon Disk Disulfoton EPA 1657 analytes EPN English Environmental Ethion Ethyl parathion GC-FPD Malathion Methyl parathion Organophosphate Pesticide Waste water

EVOLUTE® EXPRESS SPE columns and plates combine sorbent wettability with optimized SPE components, allowing better flow consistency and in many cases eliminating the need for SPE column conditioning; thus simplifying and reducing extraction processing. This poster compares the performance of various EVOLUTE EXPRESS column chemistries using 10-500 mg bed weights, in order to investigate whether sorbent conditioning and equilibration steps are truly required. ASMS 2015

Acidic Amitriptyline Atenolol Benzenesulfonic acid Bretylium Clinical Column Diethyldithiophosphate (DEDTP) Dimethylthiophosphate (DMTP) English Extrahera Forensic Hexanesulfonic acid Ketoprofen LC-MS/MS Metoprolol Mianserin Organophosphate Pesticide Over the counter pharmaceuticals Pain Management Pharma Pharmaceuticals Posters Prednisolone Procainamide Quaternary Amines Quinidine Salbutamol Sulindac Tricyclic Antidepressant Urine β-blockers

This application note was developed for the clean-up of a non-polar solvent extract of vegetable material. The methodology is applicable to a wide range of organochlorine and organophosphorus pesticides and a number of vegetable types. The analytes are relatively non-polar, and will not be strongly retained by polar/anion exchange sorbents.

Application Notes Clordane Column Dicofol Endosulfan Food Food GC-MS Organochlorines Organophosphate Pesticide Organophosphates Pesticides Vegetables

This method describes the use of EVOLUTE WAX plates and columns to extract a suite of organophosphate pesticide metabolites including dimethylphosphate (DMP), dimethylthiophosphate (DMTP), diethylphosphate (DEP), diethylthiophosphate (DETP), dimethyldithiophosphate (DMDTP) and diethyldithiophosphate (DEDTP) from human urine. The method demonstrates extraction of these small polar metabolites at urine concentrations ranging from 40 ng/mL to 400 ng/mL. resin, polymer, EVOLUTE,

Application Notes Biomarker Clinical Column Diethyldithiophosphate (DEDTP) Diethylphosphate (DEP) Diethylthiophosphate (DETP) Dimethyldithiophosphate (DMDTP) Dimethylphosphate (DMP) Dimethylthiophosphate (DMTP) LC-MS/MS Organophosphate Pesticide Urine

This application note investigates the applicability of automated solid phase extraction using the Biotage(r) Horizon 4790 extractor and DryDisk solvent drying system to extraction of a wide range of different compounds from phenols, to triazines, to organochlorine and organophosphorous pesticides spiked into tap water at a concentration of 1 ug/L.

4790 Application Notes Disk English Environmental GC-MS Organochlorine pesticides (OCP) Organophosphate Pesticide Phenols Triazine Herbicides Water

This technical note describes the use of layered SPE columns in applications where multiple suites of analytes with a broad polarity range are to be extracted simultaneously from a single water sample, such as organochlorine, triazine and organophosphate pesticides, or endocrine disrupters.

2,4,6-trichlorophenol 2,4-D 2,4-dichlorophenol 2,4-dimethylphenol 2,4-dinitrophenol 2,6-dichlorophenol 2,6-dinitro-2-methylphenol 2-methylphenol 2-nitrophenol 3-methylphenol 4-chloro-3-methylphenol 4-methylphenol 4-nitrophenol Acenapthalene Acid herbicides Ametrine Anthracene Application Notes Arachlor Atrazine Base-neutral herbicides Bentazone Benzo (g,h,i) perylene Benzo(a)anthracene Benzo(a)pyrene Benzo(b)fluoranthene Benzo(k)Fluoranthene Chrysene Column Desethyl atrazine Desisopropyl atrazine Dibenzo(ah)anthracene Dibenzylbutyl phthalate Dibutyl phthalate Diethyl phthalate Dimethyl phthalate Dioctyl phthalate English Environmental Environmental contaminants Fluoranthene Fluorene GC-MS Indeno(123-cd)pyrene Indeno(123-cd)pyrene LC-MS/MS MCPA MCPB Metribuzin Molinate Organochlorine pesticides (OCP) Organophosphate Pesticide Organophosphates PAHs Persistant organic pollutants (POP) Pesticides Phenanthrene Phenols Phthalates Polyaromatic Hydrocarbons (PAH) Polyaromatic hydrocarbons Product Notes Pyrene Water

EPA Method 8141B describes the performance based procedure to determine low ppb levels of organophosphorous pesticides in ground water. The OP pesticides are extracted using solid phase extraction (SPE) based on the procedure outlined in Method 3535A for OP pesticides by Method 8141. The analysis is performed with capillary GC using a FPD (flame photometric detector). This initial demonstration of capability was conducted using the Biotage® Horizon 4790 Automated Extractor System.

4790 Application Notes Azinphos methyl Chlorpyrifos Demeton (O&S) Diazinon Disk Disulfoton EPN English Environmental Ethion Ethyl parathion GC-FPD Ground water Malathion Methyl parathion Organophosphate Pesticide Organophosphates US EPA Method 8141