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ISOLUTE® PLD+ for PFAS
ISOLUTE® PLD+ for PFAS plates and columns provide clean, matrix free extracts for accurate, reliable quantitation of PFAS at clinically relevant levels by LC-MS/MS. Reduced PFAS levels in the product components mean that samples won’t be contaminated by the sample prep product.
Biological fluids contain matrix components such as proteins and phospholipids which can adversely impact analytical sensitivity, as well as analytical instrument performance, if not removed during sample preparation. The effective matrix scavenging approach employed by ISOLUTE® PLD+ for PFAS removes >99.9% of serum protein and phospholipids leading to cleaner extracts, improved analytical sensitivity and reduced instrument downtime.
Unlike SPE based techniques, ISOLUTE® PLD+ for PFAS utilizes a simplified ‘crash and filter’ approach to extract PFAS from biological matrices. No conditioning or wash steps are required, and time-consuming extract evaporation is eliminated.
Because ISOLUTE® PLD+ for PFAS does not rely on a catch and release mechanism to isolate PFAS from the biological matrix, analyte recovery is not limited by structural considerations.
