Synthesis workflow incorporates many steps including the chemical reaction, its work-up, evaporation, and purification. In many labs this workflow is slowed by the lack of instrumentation, either for synthesis, work-up, evaporation, and/or purification. When combined, use of all this automated instrumentation can reduce synthesis workflow from days to hours.
This paper highlights the use of an expedited organic synthesis workflow incorporating a Biotage® Initiator+ microwave reactor, a Biotage® V-10 Touch high-speed evaporator for solvent evaporation/chromatography sample prep, and automated flash chromatography with a Biotage® Selekt for purification.