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    Documents | Method Development Guidelines: Solid Phase Extraction Using Polar, Silica Based ISOLUTE® SPE Sorbents for the Extraction of Non-Aqueous Samples

    Method Development Guidelines: Solid Phase Extraction Using Polar, Silica Based ISOLUTE® SPE Sorbents for the Extraction of Non-Aqueous Samples

    The ISOLUTE® family of polar sorbents are used to extract polar organic compounds from non-polar matrixes. There are many functional groups that can exhibit polar interactions, and they have different selectivities.Some of the polar interactions that exist include dipole-dipole,dipole-induced dipole and hydrogen bonding. Polar interactions are particularly useful for the separation of molecules that are very similar in structure (e.g. structural isomers.

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