ISOLUTE® FILTER+ plates provide effective, workflow friendly filtration of diverse biological samples, and are ideal for use with urine prepared by ‘dilute and shoot’ prior to UPLC-MS/MS analysis. ISOLUTE FILTER+ plates are designed to prevent sample particulates from reaching the analytical UPLC column, protecting the analytical system from particulate build up over time. Increased back pressures due to particulate accumulation necessitate frequent downtime for replacement or regeneration of the expensive analytical column.
The plates contain a wettable 0.2 µm membrane filter for high performance particulate removal, topped by a depth filter to prevent blocking of the membrane, and can be processed using manual or automated positive pressure or vacuum manifold processing systems. The plate outlet penetrates into the collection plate to prevent sample cross talk.
Filtered samples will be particulate free and visually clearer.