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    Documents | Fast Extraction of Metanephrine and Normetanephrine from Pooled Plasma Using EVOLUTE® EXPRESS WCX in a 96-Well Plate Format Prior to LC-ESI-MS/MS

    Fast Extraction of Metanephrine and Normetanephrine from Pooled Plasma Using EVOLUTE® EXPRESS WCX in a 96-Well Plate Format Prior to LC-ESI-MS/MS

    This application note describes a method of extraction for metanephrine and normetanephrine from pooled plasma using EVOLUTE® EXPRESS WCX 96-well SPE plates. A new solid phase extraction technology has been developed to reduce the time associated with sample preparation methods by eliminating traditional steps in the extraction workflow. Leveraging this technology, a method protocol was developed using a load, wash and elute approach. This method was optimized for pooled plasma.

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