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    Documents | Extraction of THC and its Metabolites from Human Hair Using ISOLUTE® SLE+ Prior to UPLC-MS/MS Analysis

    Extraction of THC and its Metabolites from Human Hair Using ISOLUTE® SLE+ Prior to UPLC-MS/MS Analysis

    This application note describes a procedure for sample pre-treatment and extraction of THC and metabolites from human hair, using Biotage® Lysera for matrix pulverization of the sample prior to clean up using ISOLUTE® SLE+ supported liquid extraction. Manual processing protocols were developed using the Biotage® PRESSURE+ 96 (plate format) or 48 (column format) positive pressure manifolds. For automated processing, protocols were developed using Biotage® ExtraheraTM.

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