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    Documents | Automated Extraction of Synthetic Cannabinoids (SPICE) from Urine using ISOLUTE® SLE+ Prior to LC-MS/MS

    Automated Extraction of Synthetic Cannabinoids (SPICE) from Urine using ISOLUTE® SLE+ Prior to LC-MS/MS

    This application note describes the extraction of a range of SPICE drugs and metabolites in urine which are typically screened in forensic toxicology panels using ISOLUTE® SLE+ in a 96-well plate format. Both manual (Biotage Pressure+ 96) and automated (TECAN Freedom EVO® 100) processing conditions are described.

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