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Scaling-up with Metal Scavengers
Small Molecules and Synthetic Therapeutics
Blog on how to implement metal scavenging, such as removal of palladium from an intermediate or API and build compliance with ICHQ3D into a ...
Practical Lab methods for the development of metal removal processes
Small Molecules and Synthetic Therapeutics
Learn how to implement metal scavenging, such as removal of palladium from an intermediate or API and build compliance with ICHQ3D into a ...
How to Remove Palladium in three easy steps
Small Molecules and Synthetic Therapeutics
How to implement metal scavenging, such as removal of palladium from an intermediate or API and build compliance with ICHQ3D into a process.
What is metal scavenging and what are metal scavengers?
Small Molecules and Synthetic Therapeutics
This guide explains what metal scavengers are and shows how to use the gold standard Biotage MP-TMT in the removal of palladium from API / ...
Can biological assay results be trusted if your sample is contaminated with Pd?
Small Molecules and Synthetic Therapeutics
Research showing palladium makes it way to final products from medchem routes and this interferes with biological screens. Biotage® Si-TMT ...
Exploding the myth about loading capacity and metal scavengers
Small Molecules and Synthetic Therapeutics
Research showing palladium makes it way to final products from medchem routes and this interferes with biological screens. Biotage® Si-TMT ...
Are metal scavengers better than carbon?
Small Molecules and Synthetic Therapeutics
A look at why activated carbon may not be best for removing metals. Using Biotage® Si-Thiol, we did not lose yield, the reaction was easy ...
Why we should be wary of alternatives to the original, trusted Biotage ISOUTE® Si-Thiol metal scavenger
Small Molecules and Synthetic Therapeutics
This blog post discusses why we should be wary of alternatives to the original, trusted Biotage ISOUTE® Si-Thiol metal scavenger.
Can I use TLC for reversed-phase flash column chromatography method development?
Small Molecules and Synthetic Therapeutics
This post explains why reversed-phase TLC is not the best choice for reversed-phase flash method development.
How do I develop a reversed-phase flash column chromatography method?
Small Molecules and Synthetic Therapeutics
How do I develop a reversed-phase flash column chromatography method?
