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Does Detection Wavelength Influence Compound Purity and Recovery?
Small Molecules and Synthetic Therapeutics
This post discusses whether a single or multiple fractionation wavelengths generate higher purity in greater amounts.
When should I use a “high-performance" flash chromatography column?
Small Molecules and Synthetic Therapeutics
This post discusses the benefits achievable when using a “high-performance" flash chromatography column.
TLC-based vs. Generic Gradients – Which Gives the Best Results?
Small Molecules and Synthetic Therapeutics
This post compares TLC-based gradients to a generic linear gradient to highlight the benefits TLC provides.
Ionizable compound purification using reversed-phase flash column chromatography
Small Molecules and Synthetic Therapeutics
This post discusses how ionizable compounds can be purified using reversed-phase flash column chromatography.
Does a longer flash column really provide better purification?
Small Molecules and Synthetic Therapeutics
This post discusses the relationship between column length and column diameter and their impact of chromatographic separations.
5 Steps to successful flash chromatography
Small Molecules and Synthetic Therapeutics
This post discusses the 5 most important steps to successful flash chromatography.
How do particle size and flow rate affect normal-phase flash column chromatography
Small Molecules and Synthetic Therapeutics
This blog describes the impact of particle size and flow on the loading capacity of a flash chromatography column.
Why is TLC Rf important for flash column chromatography optimization?
Small Molecules and Synthetic Therapeutics
This post discussed the reasons TLC Rf values are important for flash column chromatography optimization.
Why does my silica flash chromatography column get hot?
Small Molecules and Synthetic Therapeutics
The post discusses the reasons dry silica columns get hot when solvent is introduced and the impact the generated heat has on the resulting ...
How does solvent choice impact flash column chromatography performance?
Small Molecules and Synthetic Therapeutics
How does solvent choice impact flash column chromatography performance?
