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The three reasons you should be using step gradients for flash column chromatography
Small Molecules and Synthetic Therapeutics
Step gradient flash chromatography improves loading capacity, while reducing solvent use and overall purification time.
Greener flash chromatography tips
Small Molecules and Synthetic Therapeutics
Green flash chromatography is achievable and inexpensive. Using columns packed with small, high surface area silica is the simplest way to ...
Dry loading media options – diatomaceous earth
Small Molecules and Synthetic Therapeutics
Diatomaceous earth is an excellent media for dry loading in both normal- and reversed-phase flash chromatography.
How many ways can you load sample on your column?
Small Molecules and Synthetic Therapeutics
Dry loading can give better results in chromatography sometimes compared to liquid loading. Read more!
A Workflow for Academic Drug Discovery - Baylor University Customer Case
Small Molecules and Synthetic Therapeutics
This article discusses the impact of introducing the Biotage Organic Workflow into a university laboratory via an interview with Director ...
How to minimize particulate build-up in flash chromatography systems
Small Molecules and Synthetic Therapeutics
Sometimes during flash chromatography the system will overpressure due to a flow blockage. This post provides some tips to prevent this ...
What are good reversed-phase dry load options?
Small Molecules and Synthetic Therapeutics
This blog will help you understand dry loading, a sample loading technique that uses a blend of reaction mix/extract and sorbent.
What is Flash Chromatography and why should I do it?
Small Molecules and Synthetic Therapeutics
This is a basic overview of what flash chromatography is and why it is useful to chemists.
Flash column chromatography equilibration speed – how fast can you go?
Small Molecules and Synthetic Therapeutics
Flash column equilibration is important to ensure a proper separation occurs. This post discusses the impact of flow rate and equilibration ...
Prep HPLC vs. reversed-phase flash chromatography: How to choose?
Small Molecules and Synthetic Therapeutics
This post discusses the differences between RP flash and prep HPLC for compound purification.
