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Using microwave heating for your stapled peptide synthesis
Small Molecules and Synthetic Therapeutics
Ring-closing metathesis has gained a lot of attention for use in peptide stapling strategies. Read more to learn how microwave heating can ...
How To: Measure and Optimize the Removal of MMT Protecting Groups
Small Molecules and Synthetic Therapeutics
Ensuring the complete removal of an orthogonal protecting group is the first step in optimizing on-resin secondary chemistry.
Optimizing the removal of an ACM protecting group
Small Molecules and Synthetic Therapeutics
Orthogonal protecting groups enable additional chemistry while peptides remain on the resin. Read more to learn how to remove Acm ...
Does amino acid concentration really matter during peptide synthesis?
Small Molecules and Synthetic Therapeutics
Concentration impacts the efficiency of a chemical reaction. Learn how increasing your amino acid concentration can improve your crude ...
Five Tips and Tricks for Success in Solid Phase Peptide Synthesis
Small Molecules and Synthetic Therapeutics
Read more for a short list of helpful tips and tricks to improve your peptide synthesis yield and purity.
How to purify synthetic peptides - what are the options?
Small Molecules and Synthetic Therapeutics
Synthetic peptides are often purified using RP-HPLC. Read more to learn how RP-flash chromatography could serve as an alternative.
Peptide Synthesis - What do you need to get started?
Small Molecules and Synthetic Therapeutics
Bringing peptide synthesis in-house requires some careful consideration. Read more to get a glimpse of what you'll need to get started.
Analyzing crude peptide samples by Mass Spectrometry: what are the options
Small Molecules and Synthetic Therapeutics
There are many different types of mass spetrometers and ionization methods. Read more to learn about strategies useful for analyzing ...
Increasing Productivity with Automated Flash Purification - Rice University Customer case
Small Molecules and Synthetic Therapeutics
The article describes the impact of introducing the Biotage Flash Chromatography into a university laboratory.
Preparation and use of an internal dry loading device for flash chromatography
Small Molecules and Synthetic Therapeutics
This post discusses preparation and use of flash chromatography dry loading.
