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Handling difficult peptides - how to purify beta amyloid peptides
Small Molecules and Synthetic Therapeutics
Purifying synthetic peptides can be challenging and time consuming. Read more to learn how the solvent chosen to dissolve peptides can ...
Getting started with Flash Chromatography for peptide purification - Tips and Tricks
Small Molecules and Synthetic Therapeutics
Getting started with a new technique can be challenging and even frustrating. Read more for tips and tricks as you get started using flash ...
Microwave heating - a route to better quality crude peptides
Small Molecules and Synthetic Therapeutics
The complexity of synthetic peptides continually increases. Read more to learn how microwave heating can improve your crude synthetic ...
Are there benefits to collecting flash chromatography fractions based on multiple UV wavelengths?
Small Molecules and Synthetic Therapeutics
Fractionating using multiple wavelengths simultaneously improves compound purity and yield compared to using one or two individual ...
How changing stationary phase chemistry can impact separation selectivity
Small Molecules and Synthetic Therapeutics
Removing a co-eluting impurity requires changing the purification method. Usually done with solvent change here we show the results of ...
How To Load The First Amino Acid Onto Wang Resin
Small Molecules and Synthetic Therapeutics
Wang resin is available preloaded with many amino acids, but there may be times you have to perform the chemistry yourself. Read more to ...
Can you use normal phase chromatography to purify protected peptides?
Small Molecules and Synthetic Therapeutics
Fully protected peptides can be difficult to purify using standard reversed-phase methods. Learn about normal phase chromatography as an ...
How to choose the right resin functionality for solid phase peptide synthesis
Small Molecules and Synthetic Therapeutics
There are many available resins for solid phase peptide synthesis. Read more to learn about some of the choices and how they differ from ...
Synthesis of peptides containing three disulfide bonds: can it be fully automated?
Small Molecules and Synthetic Therapeutics
In this post, we'll put to use three orthogonal protection strategies to optimize a fully automated synthesis of linaclotide.
What is solid phase peptide synthesis?
Small Molecules and Synthetic Therapeutics
What is solid phase peptide synthesis and why was it developed? Read more to learn the differences between the two main synthesis ...
