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Easy protocol to develop your Supported Liquid Extraction method
Clinical, Forensic and Doping Testing
The blog contains a step by step guide to develop a Supported Liquid Extraction method in 16 steps.
What’s the Best Way to do Supported Liquid Extraction?
Clinical, Forensic and Doping Testing
Learn more about how Supported Liquid Extraction works and the proper way to do an SLE extraction for sample clean up.
How to determine recovery and matrix effects for your analytical assay
Clinical, Forensic and Doping Testing
This blog is devoted to the mathematical relationship between the universally accepted criteria for method robustness and assay confidence.
Why is pH adjustment important for sample prep methods?
Clinical, Forensic and Doping Testing
Using the “pH rule of 2” and knowing the pH at which your analytes are charged can produce cleaner samples by using mixed mode ion exchange ...
When should I choose a mixed-mode SPE?
Clinical, Forensic and Doping Testing
This post explains the differences between anionic and cationic SPE exchange phases and how optimize an extraction protocol using them.
When should I choose weak ion exchange SPE phases?
Clinical, Forensic and Doping Testing
SPE of strong acids and bases is done by mixed mode weak ion exchange, using pH to change the charge state of the sorbent instead of the ...
When should I choose SLE or SPE for sample cleanup?
Clinical, Forensic and Doping Testing
This blog introduces the difference between SPE and SLE.
Choosing the best Ion Exchange Mode for Solid Phase Extraction
Clinical, Forensic and Doping Testing
This blog gives some guidelines to help you to choose the most appropriate SPE ion exchange media.
How to Monitor and Prevent Sample Carryover during Method Development
Clinical, Forensic and Doping Testing
This blog gives useful insights to learn how to monitor and prevent sample carryover during an analysis method development.
How does my sample prep change between GC/MS and LC/MS/MS?
Clinical, Forensic and Doping Testing
This blog helps to understand hot to modify a sample preparation method optimized for LC/MS-MS analysis to better fit for a GC-MS analysis.
