Blog

Small Molecules and Synthetic Therapeutics

There are many available resins for solid phase peptide synthesis. Read more to learn about some of the choices and how they differ from ...

Small Molecules and Synthetic Therapeutics

In this post, we'll put to use three orthogonal protection strategies to optimize a fully automated synthesis of linaclotide.

Small Molecules and Synthetic Therapeutics

What is solid phase peptide synthesis and why was it developed? Read more to learn the differences between the two main synthesis ...

Small Molecules and Synthetic Therapeutics

Predicting peptide elution profile is critical for efficient peptide purifications. Learn how a scouting column, with matched stationary ...

Small Molecules and Synthetic Therapeutics

Learn how to quickly and gently evaporate peptide cleavage cocktail, reducing your total peptide workflow time significantly.

Small Molecules and Synthetic Therapeutics

Methanol is increasingly used for reversed phase purification in place of acetonitrile. Learn how methanol impacts your peptide ...

Small Molecules and Synthetic Therapeutics

Cleaving peptides from resin is often a very fast reaction, however side chain protecting groups may require more time. What reaction time ...

Small Molecules and Synthetic Therapeutics

Reversed phase flash chromatography is growing in popularity as a strategy to purify crude peptide samples. Read more to how gradient ...

Small Molecules and Synthetic Therapeutics

Step gradients are often used in normal phase chromatography. Read more to learn how they can be used to also improve the purity of your ...

Small Molecules and Synthetic Therapeutics

Peptide purification with flash chromatography can be hampered by resolution losses. Read more to learn how a focused gradient can improve ...