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Can water be used as an organic synthesis solvent?
Small Molecules and Synthetic Therapeutics
This post shows that water is a suitable synthesis solvent, enabling greener chemistry.
Does reagent and reaction solvent order impact product yield and purity?
Small Molecules and Synthetic Therapeutics
This post discusses if the order in which reaction components are added impacts the synthetic product's purity and/or yield.
How does reaction time impact synthetic product purity and yield?
Small Molecules and Synthetic Therapeutics
This post discusses the impact of time on a reaction.
How does reagent concentration impact synthesis?
Small Molecules and Synthetic Therapeutics
This post discusses the impact that reagent concentration has on a synthetic product yield and purity.
How Much Is My Flash Chromatography System Really Going to Cost?
Small Molecules and Synthetic Therapeutics
How much does it cost? One of the first questions when considering an automated flash column chromatography system. Here we answer the ...
How to quantify your first amino acid loading onto Wang resins
Small Molecules and Synthetic Therapeutics
Occassionally, peptide chemists still have to couple the first amino acid onto Wang-type resins. Read more to learn how to quantify the ...
How does gradient slope impact flash chromatography loading capacity?
Small Molecules and Synthetic Therapeutics
This post shows how gradient slope optimization increases sample loading.
How to Purify your Target Compound with Minimal Impurities
Small Molecules and Synthetic Therapeutics
This post describes various flash chromatography options available for targeted compound purification.
What is the best way to purify a crude reaction mixture that auto-crystallizes?
Small Molecules and Synthetic Therapeutics
This post discusses the benefits of purifying the full precipitated reaction mix vs. filtration, phase separation, redissolution and ...
What are alternatives to DCM/MeOH for polar reaction mix purifications?
Small Molecules and Synthetic Therapeutics
This post describes alternatives to DCM/Methanol for polar compound purification.
