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Small Molecules and Synthetic Therapeutics

The overall hydrophobicity of a peptide can severely limit the synthesis success. Read more to learn how choosing an alternative system ...

Small Molecules and Synthetic Therapeutics

Purifying synthetic peptides can be challenging and time consuming. Read more to learn how the solvent chosen to dissolve peptides can ...

Small Molecules and Synthetic Therapeutics

Getting started with a new technique can be challenging and even frustrating. Read more for tips and tricks as you get started using flash ...

Small Molecules and Synthetic Therapeutics

The complexity of synthetic peptides continually increases. Read more to learn how microwave heating can improve your crude synthetic ...

Small Molecules and Synthetic Therapeutics

Wang resin is available preloaded with many amino acids, but there may be times you have to perform the chemistry yourself. Read more to ...

Small Molecules and Synthetic Therapeutics

Fully protected peptides can be difficult to purify using standard reversed-phase methods. Learn about normal phase chromatography as an ...

Small Molecules and Synthetic Therapeutics

There are many available resins for solid phase peptide synthesis. Read more to learn about some of the choices and how they differ from ...

Small Molecules and Synthetic Therapeutics

In this post, we'll put to use three orthogonal protection strategies to optimize a fully automated synthesis of linaclotide.

Small Molecules and Synthetic Therapeutics

What is solid phase peptide synthesis and why was it developed? Read more to learn the differences between the two main synthesis ...

Small Molecules and Synthetic Therapeutics

Predicting peptide elution profile is critical for efficient peptide purifications. Learn how a scouting column, with matched stationary ...