Extracting both acidic and basic analytes in a single SLE procedure
Often the question arises asking how can I extract both acids and bases with the same Supported Liquid Extraction (SLE) procedure. Is this possible? And how?
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Showing posts written by Bruce Kempf
Easy protocol to develop your Supported Liquid Extraction method
Taking the time to develop a Supported Liquid Extraction (SLE) method using easy steps can save you hours or days of headaches down the road as well as giving you the peace of mind that you’re getting...
When should I choose SLE or SPE for sample cleanup?
When it comes to sample cleanup the question occasionally comes up asking what technique is best for my application: Solid Phase Extraction (SPE) or Supported Liquid Extraction (SLE)? Well, what’s rig...
Choosing the best Ion Exchange Mode for Solid Phase Extraction
There is often confusion as to how to choose the proper SPE ion exchange media. How do you determine if you should be looking at anion or cation, weak or strong? In this post, I will give some simple ...
Techniques for disrupting protein binding in sample preparation
If you are frustrated with low recoveries caused by protein binding during Supported Liquid Extraction (SLE) and Solid Phase Extraction (SPE), this blog post will give you a few tips. Proper sample pr...