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How does media pore size impact small-molecule flash column chromatography?
Small Molecules and Synthetic Therapeutics
This post discussed the impact of media pore size on small-molecule flash column chromatography.
Can reversed-phase chromatography compound elution volume/time be predicted?
Small Molecules and Synthetic Therapeutics
This posts describes tips to improve reversed-phase method development.
When should I add acid to my detector make-up solvent when using mass-directed flash chromatography?
Small Molecules and Synthetic Therapeutics
When should I add acid to my detector make-up solvent when using mass-directed flash chromatography?
Invest 10 minutes on TLC and save a day of grief
Small Molecules and Synthetic Therapeutics
This post discusses the benefits of spending only 10 minutes developing TLC data to support optimized flash chromatography.
Does high performance flash column chromatography require high performance TLC for method development?
Small Molecules and Synthetic Therapeutics
Does high performance flash column chromatography require high performance TLC for method development?
Does mass detection make-up solvent choice matter?
Small Molecules and Synthetic Therapeutics
Does mass detection make-up solvent choice matter?
How do I convert my HPLC method to flash chromatography?
Small Molecules and Synthetic Therapeutics
This post discusses the best options for creating and transferring HPLC-based methods to flash chromatography.
Acetone – a lower cost alternative to EtOAc in normal-phase flash column chromatography
Small Molecules and Synthetic Therapeutics
This post discusses the benefits of acetone over ethyl acetate in normal-phase flash chromatography.
Using pH to optimize reversed-phase flash chromatography separations
Small Molecules and Synthetic Therapeutics
Using pH to optimize reversed-phase flash chromatography separations.
In-line mass detection to find the undetectable in flash column chromatography
Small Molecules and Synthetic Therapeutics
This post describes the benefits of in-line mass detection to find the undetectable compounds when using flash chromatography.
