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Small Molecules and Synthetic Therapeutics

This post discusses the differences between linear gradients and step gradients for flash chromatography.

Small Molecules and Synthetic Therapeutics

Sample loading techniques, whether liquid or dry, greatly influence purification results.

Small Molecules and Synthetic Therapeutics

This post talks about the chemical interactions that take place in order to selectively separate compounds from each other.

Small Molecules and Synthetic Therapeutics

This post provides some guidelines on choosing between flash chromatography techniques.

Small Molecules and Synthetic Therapeutics

This post discusses an alternative purification approach using a amine-functionalized silica.

Small Molecules and Synthetic Therapeutics

This post discusses the use of both normal- and reverse-phase flash chromatography to purity polar cannabinoids such as CBG from hemp.

Small Molecules and Synthetic Therapeutics

This post discusses the benefits of using TLC to scout various flash chromatography solvents.

Small Molecules and Synthetic Therapeutics

This post describes a flash chromatographic method for the purification of CBN from a crude reaction mixture.

Small Molecules and Synthetic Therapeutics

This post discusses how CBC can be purified from a hemp extract using flash chromatography.

Small Molecules and Synthetic Therapeutics

There will be times when standard silica normal-phase flash chromatography just will not work. When this happens, explore reversed-phase.