Rapidly synthesize high quality peptides using microwave irradiation. A cost effective and versatile accessory for manual microwave peptide synthesis and cleavage when used with a Biotage® Initiator+ microwave synthesizer.
Biotage® Initiator+ represents the latest in microwave synthesis performance. This instrument’s high-end specifications enable the chemist to explore new areas and perform the latest of innovations in chemistry. A reliable and upgradeable platform that allows chemists to make great discoveries in less time.
Biotage® Initiator+ Alstra™ is a fully automated microwave peptide synthesizer . With functionality such as Branches, Preactivation and “Edit on the fly”, and options for UV monitoring and MAOS (organic synthesis) capability, this instrument represents best-in-class systems for both small and large scale synthesis of peptides, peptoids, PNA and peptidomimetics.
“The Initiator+ SP Wave – I think it’s an amazing little beast. Semi-automated, which I think is ideal for an academic lab making lots of bizarre peptides and exotics on a day-to-day basis then it’s a fantastic instrument. You can make PNA and ours has worked amazingly well in terms of the purity of materials obtained” Prof Mark Bradley, School of Chemistry, University of Edinburgh
Biotage® Initiator+ can be upgraded from a single-sample manual format to an automated 8- or 60-position system. The modular design allows a user to add on different automated sample processors dependent on throughput requirements.
Biotage® Syro Wave™ is the only programmable peptide synthesizer that is capable of both conventional room temperature parallel peptide synthesis and microwave assisted peptide synthesis. The system is fully automated and computer controlled utilizing a pipetting robot with a single arm. Now available with the new Syro Heating Block(s) option!
Biotage® V-10 Touch rapidly dries samples dissolved in both aqueous and organic solvents. It easily evaporates HPLC fractions from purification, high boiling point solvents from synthesis and features a novel dry-down onto silica technique for easier dry load capabilities prior to purification.
For peptides acid, we recommend using the HMPB-ChemMatrix as this resin will provide high crude purity and a recovery yield of 90-95%. The Wang-ChemMatrix will produce similar crude peptide purity, but the recovery yield is lower (60-70%). On request, we can provide preloaded HMPB-ChemMatrix resins with all 20 naturally occurring amino acids. Other amino acids can be preloaded on special request.
Fully automated computer controlled peptide synthesizer based on a one arm pipetting robot. Syro I is equipped with one type-U reactor block that can accept 2, 5 and 10 ml reactors. An infinitely variable vortexer guarantees an optimal mixing of the reactants. Now available with the new Syro Heating Block(s) option!
Trityl-ChemMatrix is mainly used to obtain a protected peptide as is has very low TFA cleavage conditions (under 1%). This resin therefore has the same cleavage conditions as the Cl-Trityl-polystyrene. On request, Trityl-ChemMatrix resins can be offered preloaded will all 20 natural amino acids. Other amino acids can be preloaded on special request. Please take note that the Cl-Trityl-ChemMatrix resin is not offered for stability reasons. It is most effective to start with the Trityl-OH-ChemMatrix resinchlorinate the resin and then add the amino acid of desire.