Rapidly synthesize high quality peptides using microwave irradiation. A cost effective and versatile accessory for manual microwave peptide synthesis and cleavage when used with a Biotage® Initiator+ microwave synthesizer.
Biotage® Initiator+ represents the latest in microwave synthesis performance. This instrument’s high-end specifications enable the chemist to explore new areas and perform the latest of innovations in chemistry. A reliable and upgradeable platform that allows chemists to make great discoveries in less time.
Biotage® Initiator+ Alstra™ is a fully automated microwave peptide synthesizer . With functionality such as Branches, Preactivation and “Edit on the fly”, and options for UV monitoring and MAOS (organic synthesis) capability, this instrument represents best-in-class systems for both small and large scale synthesis of peptides, peptoids, PNA and peptidomimetics.
“The Initiator+ SP Wave – I think it’s an amazing little beast. Semi-automated, which I think is ideal for an academic lab making lots of bizarre peptides and exotics on a day-to-day basis then it’s a fantastic instrument. You can make PNA and ours has worked amazingly well in terms of the purity of materials obtained” Prof Mark Bradley, School of Chemistry, University of Edinburgh
Biotage® Initiator+ can be upgraded from a single-sample manual format to an automated 8- or 60-position system. The modular design allows a user to add on different automated sample processors dependent on throughput requirements.
Biotage® V-10 Touch rapidly dries samples dissolved in both aqueous and organic solvents. It easily evaporates HPLC fractions from purification, high boiling point solvents from synthesis and features a novel dry-down onto silica technique for easier dry load capabilities prior to purification.
For peptide acids, we recommend using the HMPB-ChemMatrix as this resin will provide high crude purity and a recovery yield of 90-95%. The Wang-ChemMatrix will produce similar crude peptide purity, but the recovery yield is lower (60-70%). On request, we can provide preloaded HMPB-ChemMatrix resins with all 20 naturally occurring amino acids. Other amino acids can be preloaded on special request.
Durable and safe reactions at all times. Our high precision microwave vials are designed and tested to withstand pressures beyond 30 bar in a wide range of conditions. NOTE: Biotage® Microwave Reaction Vials (in combination with the caps and septa) are ONLY to be used in Biotage Microwave Synthesizers.
Fully automated computer controlled peptide synthesizer based on a one arm pipetting robot. Syro I is equipped with one type-U reactor block that can accept 2, 5 and 10 ml reactors. An infinitely variable vortexer guarantees an optimal mixing of the reactants. Now available with the new Syro Heating Block(s) option!
Trityl-ChemMatrix is mainly used to obtain a protected peptide as is has very low TFA cleavage conditions (under 1%). This resin therefore has the same cleavage conditions as the Cl-Trityl-polystyrene. On request, Trityl-ChemMatrix resins can be offered preloaded will all 20 natural amino acids. Other amino acids can be preloaded on special request. Please take note that the Cl-Trityl-ChemMatrix resin is not offered for stability reasons. It is more effective to start with the Trityl-ChemMatrix resin, chlorinate the resin and then add the amino acid required.