EVOLUTE® SPE Columns and Plates

Processing samples using EVOLUTE® EXPRESS columns or plates with a simplified Load-Wash-Elute procedure can increase productivity by eliminating the need for the conditioning and equilibration steps. This is made possible due to the combination of the water wettable EVOLUTE® sorbents and the aqueous compatible plate components incorporated in EVOLUTE® EXPRESS.

For most applications the Load-Wash-Elute procedure gives the same high analyte recoveries and low variability as standard SPE but can reduce processing time by one third.

EVOLUTE® EXPRESS products dramatically improve flow characteristics and enhance sample preparation productivity. Flow rates are fast and consistent even when loading aqueous biological fluid sample directly onto a dry column.

Specially treated inert, hydrophilic frits, water wettable polymeric EVOLUTE sorbents and the exact dimensions and packing techniques all work together to give you extremely consistent results, batch to batch.

All EVOLUTE sorbents have a high surface area to ensure high, reproducible analyte recoveries.  But, to achieve the highest sensitivity in LC-MS/MS analyses, its important to reduce or eliminate matrix components that cause ion suppression.  In biological fluids, one of the main causes is proteins that are co-extracted from the sample.

EVOLUTE sorbents have an optimized pore diameter (approximately 40 Å) which is narrower than most other polymeric SPE sorbents.  This narrow pore size prevents larger protein molecules from retaining on the SPE column or plate during the SPE process, so they don't end up in the extract, and more importantly, don't cause matrix effects in the LC-MS/MS.

Unlike other polymeric brands, EVOLUTE® EXPRESS combines a cleaner SPE sorbent with optimised components, making sample prep simple and more consistent from sample-to-sample.

EVOLUTE® EXPRESS ABN

• For simultaneous extraction of acidic, basic and/or neutral analytes 

EVOLUTE® EXPRESS CX

• For extraction of basic analytes

EVOLUTE® EXPRESS WCX

• For extraction of strongly basic analytes

EVOLUTE® EXPRESS AX

• For extraction of acidic analytes 

EVOLUTE® EXPRESS WAX

• For extraction of strongly acidic analytes