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SPE Columns

Biotage sample preparation column size table

ISOLUTE® PSA is a weak anion exchange sorbent used to extract strong acids and polyacidic compounds from aqueous samples.

Alternatively, it can be used as a polar sorbent to extract polar analytes from non-aqueous matrices.


Part No. Description Product type Pack Size Price
480-0020-B 480-0020-B ISOLUTE® PSA 200 mg/3 mL Consumables 50 Log in for price
480-0050-B 480-0050-B ISOLUTE® PSA 500 mg/3 mL Consumables 50 Log in for price
480-0050-C 480-0050-C ISOLUTE® PSA 500 mg/6 mL Consumables 30 Log in for price
480-0100-C 480-0100-C ISOLUTE® PSA 1 g/6 mL Consumables 30 Log in for price
9480-0100 9480-0100 ISOLUTE® PSA Bulk 100 g Consumables 1 Log in for price

Structure of ISOLUTE PSA 

ISOLUTE® PSA is an ethylenediamine-n-propyl bonded sorbent sorbent used for the extraction of strongly acidic compounds (e.g. those containing sulfonic acid groups) or analytes unstable under acidic conditions, from aqueous samples using a weak anion exchange retention mechanism.   It can also be used to complex with certain metal cations. Analyte elution can be performed by neutralizing charge on the sorbent (high pH). The sorbent is supplied as the free base.

Alternatively, ISOLUTE PSA can be used for extraction of polar compounds from a non-polar matrix using a hydrogen bonding retention mechanism. It is less retentive than ISOLUTE SI.

ISOLUTE PSA is available in a wide range of SPE columns formats.

ISOLUTE PSA is also available as loose sorbent (100g pack).