|Chemical description||Octyl (C8, non-endcapped) and carboxylic acid (COO-)|
|Average particle size||50 µm|
|Pore diameter||60 Å|
This method describes the extraction of quaternary amines, strongly basic amines and amines that are unstable at high pH levels, from biological fluids. The mechanism is mixedmode
hydrophobic and weak cation exchange, allowing acidic elution conditions.
Tags: Application Notes, Biological fluids, Clinical, Quaternary Amines
In this catalog product information is displayed with easy-to-follow application details and supporting documentation.
Ordering information is found following each product listing.
The first decision that needs to be made is what the final analysis will be for the analyte. This will have an impact on the sample and cartridge size, as well as the final elution solvent. Gas chromatography offers higher sensitivity than HPLC, while HPLC is better suited for ionisable species and very high molecular weights. If LC-MS is available, minimal sample clean-up may be required.
Tags: Manuals & User Guides
The ISOLUTE® HCX-Q SPE sorbent has been developed for the extraction of quaternary amines and polybasic
drugs from biological fluids, giving high reproducible recoveries and clean extracts.
Tags: Product Notes
The use of ISOLUTE HCX mixed-mode sorbents is widely accepted for providing high purity extracts of basic drugs from biological fluids. The ISOLUTE HCX-Q sorbent utilizes a combination of weak cation exchange and C8 non-polar retention mechanisms.
Tags: Product Notes
Biotage will attend SFTA, Avignon, France. 9th - 12th May, 2017 Read more http://www.sfta.org/img/uploads/2016/11/MENU_DE_PARTENARIAT_SFTA_2017.pdf03 May 2017
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This application note describes the operating conditions for the automated fractionation of EPH into aliphatic and PAH fractions using the ISOLUTE® EPH column in conjunction with the Biotage&re...20 February 2017
This application note describes the extraction of 49 drugs of abuse from whole blood, prior to UPLC-MS/MS analysis. An effective and efficient ISOLUTE SLE+ protocol optimized the for ...05 January 2016
Now available, the Biotage 2016 catalog of analytical sample preparation products for chemistry professionals. This edition includes a comprehensive range of products for bioanalysis, forensic, cli...11 August 2015
Dilute and shoot (D&S) methods are promoted for use by analytical instrument vendors in clinical, forensic toxicology and bioanalytical laboratories. More sensitive LC-MS/MS systems make this s...27 March 2015
Biotage, pioneers in flash chromatography, started packing columns with silica for flash purification 30 years ago. Some of the first employees are still with us today. In this video, site director...08 January 2015
Now available, the Biotage 2015 catalog of analytical sample preparation products for chemistry professionals. This edition includes a comprehensive range of products for bioanalysis, forensic, cli...29 July 2014
Buy your Biotage consumables through our website and shipping is free For a limited time, free shipping is applied to Biotage consumables orders through the Biotage website*. Let Biotage make orde...
What is the maximum capacity of an SPE column?
The capacity of a sorbent is defined as the total mass of strongly retained analyte that can be retained by a given mass of the sorbent under optimum conditions.
For most sorbents, this can range from 1-5% by weight. 100 mg of sorbent might retain 1-5 mg of analyte.
Ion exchange sorbents typically have a capacity of 0.3-1 meq/g.Browse more questions and answers >
|Part No.||Description||Product type||Pack Size||Price|
|986-0002-A||ISOLUTE HCX-Q 25 mg/1 mL||Consumables||100||Log in for price|
|986-0005-A||ISOLUTE HCX-Q 50 mg/1 mL||Consumables||100||Log in for price|
|986-0010-A||ISOLUTE HCX-Q 100 mg/1 mL||Consumables||100||Log in for price|
|986-0025-P01||ISOLUTE-96 HCX-Q 25 mg plate||Consumables||1||Log in for price|
|986-0100-P01||ISOLUTE-96 HCX-Q 100 mg plate||Consumables||1||Log in for price|