|Chemical description||Primary/secondary amine modified polystyrene-divinylbenzene incorporating non-ionizable hydroxyl groups|
|Sorbent type||Mixed-mode non-polar/weak anion exchange|
|Exchange capacity||0.3 mmol/g|
|Average particle size||30 µm, 50 µm|
|Pore diameter||40 Å|
This application note describes a Biotage polymer-based mixed-mode weak anion exchange SPE protocol for the extraction of a range of polyfluorinated (PFA) compounds in water prior to LC-MS/MS detection.
High (>80%) reproducible analyte recoveries, with excellent linearity to LOQs of 0.1 ng/L or below are achieved.
Tags: Application Notes, Column, English, Environmental, LC-MS/MS, Perfluorobutanesulfonic acid (PFBuS), Perfluorodecanoic acid (PFDA), Perfluoroheptanoic acid (PFHpA), Perfluorohexanesulfonic acid (PFHxS), Perfluorohexanoic acid (PFHxA), Perfluorononanoic acid (PFNA), Perfluorooctanesulfonic acid (PFOS), Perfluorooctanoic acid (PFOA), Persistant organic pollutants (POP), Polyfluorinated acids, Water
This method describes the use of EVOLUTE WAX plates and columns to extract a suite of organophosphate pesticide metabolites including dimethylphosphate (DMP), dimethylthiophosphate (DMTP), diethylphosphate (DEP), diethylthiophosphate (DETP), dimethyldithiophosphate (DMDTP) and diethyldithiophosphate (DEDTP) from human urine. The method demonstrates extraction of these small polar metabolites at urine concentrations ranging from 40 ng/mL to 400 ng/mL.
resin, polymer, EVOLUTE,
Tags: Application Notes, Clinical, Column, Diethyldithiophosphate (DEDTP), Diethylphosphate (DEP), Diethylthiophosphate (DETP), Dimethyldithiophosphate (DMDTP), Dimethylphosphate (DMP), Dimethylthiophosphate (DMTP), LC-MS/MS, Organophosphate Pesticide, Urine
This poster uses gel electrophoresis data to visually illustrate the amount of residual protein in extracts prepared using protein precipitation, supported liquid extraction and various silica and polymer based SPE approaches.
Tags: Biological fluids, English, HPLC, LC-MS/MS, Plasma, Posters
This poster will demonstrate SPE sample preparation strategies for the simultaneous extraction of both ethyl glucuronide and ethyl sulphate from urine, allowing cleaner extraction protocols compared to traditional dilute and shoot approaches.
EtG, EtS, Urine, Poster, SOFT, Forensic, UPLC, LC-MS/MS, EVOLUTE, AX, WAX
Tags: 96-well plate, Alcohol metabolite, Column, Ethyl Sulfate (EtS), Ethyl glucuronide (EtG), Forensic, LC-MS/MS, Posters, Urine