Item added to cart
Shopping Cart (Login required)
Sample Preparation Organic Synthesis Peptide Chemistry Flash Purification Work-up Products Evaporation Process Development Industrial Products Service & Support

Biotage® Flash 150 System

Purify up to 500 g of product per run at 1L/min

Flash 150_Front Page
Flash 150 system Flash 150 Cartridges 150_system_illustration

The Biotage® Flash 150 system supports batch purification up to 80% faster than traditional glass columns. Flash 150 is a simple, robust and reliable system, containing everything needed for large or industrial scale separations.

INSTRUMENTS

Part No. Description Product type Pack Size Price
SF-022-25071 Flash 150M system Instruments 1 Log in for price
SF-022-25151 Flash 150L system Instruments 1 Log in for price

ACCESSORIES

Part No. Description Product type Pack Size Price
FB-012-25070 Flash 150M Radial Compression Barrel Accessories 1 Log in for price
FB-012-25150 Flash 150L Radial Compression Barrel Accessories 1 Log in for price
FC-022-25071 Flash 150M Radial Compression Module Accessories 1 Log in for price
FC-022-25151 Flash 150L Radial Compression Module Accessories 1 Log in for price
FGD-15075 Kit, Grounding Assembly Flash Accessories 1 Log in for price
FIV-VLV-1000 Valve, 3-Way injection valve for Flash 75/150 systems Accessories 1 Log in for price
FN-004-41201 4 Litre Solvent Reservoir Accessories 1 Log in for price
FN-012-41201 12 Litre Solvent Reservoir Accessories 1 Log in for price
FN-037-41200 37 Litre Solvent Reservoir Accessories 1 Log in for price
FN-060-41200 60 Litre Solvent Reservoir Accessories 1 Log in for price
SIM-1002 SIM 1000 Accessories 1 Log in for price
SIM-2002 SIM 2000 Accessories 1 Log in for price

Reliable Scale-up – Faster 

Biotage® Flash 150 systems safely operate at 100 psi enabling fast flow rates and the use of high viscosity solvents. Our proven, patented radial compression technology ensures near zero “wall effects” and channelling inside each column. This maintains the bed’s stability, rendering cleaner, purer fractions in less time and higher overall product yield. Routinely operating at a flow rate of up to 1L/min, these purification systems allow you to quickly scale-up and complete runs, saving hours or even days of purification time.

80% Time Saving

In a comparison between a Flash 150M cartridge (150 mm x 300 mm) and a 120 mm x 660 mm traditional glass column, fractions were collected in 7.2 hours using the glass column, while the Flash 150M cartridge required just 90 minutes. Additionally, the recovery ratio of product from the Flash 150M system was 4 times that of the glass column. This resulted in a plant saving nearly 4 weeks of development time.

 

Flash 150M

Glass Column

Column Size (mm)

150 x 300

120 x 660

Silica Quantity (kg)

2.5

3

Sample Load Mass (g)

180

450

Flow Rate (mL/min)

500

70

Total # Fractions to Collect

45

30

Purification Time (min)

90

430

Pure Compound Per Run (g)

70.5

45

Recovery Ratio (%)

87

22

Purification Throughput (g/hr)

120

63

 

Complete Kit

The Biotage® Flash 150 system includes an easy-to-install radial compression module, a fully integrated air manifold, solvent reservoir, sample injection module (SIM), a start-up kit with all necessary tubing, grounding kit, and a user’s manual. Prepacked cartridges are ordered separately. Flash 150 compression modules are mounted onto robust portable bases (included in the system package), which are fitted with casters for easy mobility.

Dependable and Flexible

All Biotage 150 cartridges are constructed of medium-density polyethylene to resist cracking and splitting and meet the FDA extractables requirement specified in 21 CFR 177.1520. There is no breakable glass, and all of the silica is completely self-contained, eliminating any exposure to silica dust or contaminants. A variety of accessories, including sample injection modules, solvent reservoirs, compression module barrels are available to maximum convenience, utility and safety of the system. 

Committed to preserving our shared environment – further details available on request.

Manufacture of consumables is accredited by the world renowned British Standards Institute.

Flexible supply chains, back up manufacturing and warehousing ensures supply risk reduction

Products which are scaleable from lab or development to process scale.

Can be used in processes in compliance with GLP standards.

For more information download the Industrial Product Portfolio Catalog.