Item added to cart
Shopping Cart (Login required)
Sample Preparation Organic Synthesis Peptide Chemistry Flash Purification Work-up Products Evaporation Process Development Industrial Products Service & Support

Biotage® ELSD-A120

Evaporative Light-scattering Detector

ISO-ELSD-A120
ISO-ELSD-A120 ISO-ELSD-A120

Biotage® ELSD (evaporative light-scattering detector) is a universal detector designed for use with Isolera™ flash purification systems when purifying organic compounds that are undetectable UV or visible light.

INSTRUMENTS

Part No. Description Product type Pack Size Price
ISO-ELSD-A120 Biotage ELSD-A120 Detector System, Complete with tubing Instruments 1 Log in for price

SERVICE & SUPPORT

Part No. Description Product type Pack Size Price
SER-ELSD-FYMP First Year Maintenance Package ELSD Detector Service & Support 1 Log in for price

ACCESSORIES

Part No. Description Product type Pack Size Price
414126 Biotage A120 ELSD Assembly Kit Accessories 1 Log in for price

SPARE PARTS

Part No. Description Product type Pack Size Price
ELSD-0890-0300 Analogue Output Cable Spare parts 1 Log in for price
ELSD-0890-0305 Gas Inlet Tube Spare parts 1 Log in for price
ELSD-0890-0315 Waste Hose (Tygon) 7cm Spare parts 1 Log in for price
ELSD-0890-0320 Solvent Waste Container (500ml) Spare parts 1 Log in for price
ELSD-0890-0345 I/O Cable Spare parts 1 Log in for price
ELSD-0890-0390 ELSD Nebuliser Spare parts 1 Log in for price
ELSD-0890-0395 Leak Sensor Assembly Spare parts 1 Log in for price

Flash chromatography with detection and fractionation is now possible when purifying carbohydrates, steroids, lipids, terpenes and other UV-transparent compounds. The ELSD-A120 is the replacement to the popular ELSD-1080 universal detector designed for use with Isolera™ flash purification systems when purifying organic compounds that are undetectable with UV or visible light.

Advanced Design

Organic compounds have different chemical and physical properties and they impact detection, even with an ELSD. Biotage® ELSD-A120 provides intelligent method design which enables the chemist to independently set nebulizer and evaporator temperatures for a particular compound or compound class. Independent temperature control helps ensure that all compounds are detected.

How Does ELSD Work?

Sample eluting from a flash cartridge enters the ELSD where it is mixed with compressed nitrogen to nebulizer the sample (creates small droplets). The nebulizer is heated and begins to evaporate the solvent and the nitrogen pushes the sample into a heating chamber where the remaining solvent is evaporated leaving small sample particles in the nitrogen stream. While migrating through the evaporator, light is shone perpendicular to the “sample flight path” and a sensor measures how much light is coming through. Loss of light transmission is proportional to the amount of compound. This information is then relayed to the Isolera where it is then collected.

Compounds eluting from a flash cartridge enter the ELSD-A120 where they are mixed with nitrogen to nebulize the sample components creating small droplets. The nebulizer is heated and begins to evaporate the solvent and the nitrogen carries the sample, the remaining solvent is evaporated leaving small sample particles in the nitrogen stream. While migrating through the evaporator, light is shone perpendicular to the “sample flight path” and a sensor measures how many particles are present and triggering fraction collection.

  • Application Areas
  • Carbohydrates
  • Lipids
  • Steroid
  • Terpenes
  • Oils
  • Natural Products

Features

  • Flexibility – high sensitivity provides superb responses for all compounds, able to detect virtually any compound 
  • Ambient operation – provides detection capability a range of compounds with operation from Ambient temperature up to 120 °C 
  • Reproducible - below 2% with reliable and accurate results 
  • Independent temperature controls – for both nebulizer and evaporator provides optimization capability for normal phase solvent systems 
  • Compact size – requires minimal bench space 
  • Compatible and portable – operates with other analytical HPLC systems