Flash Cartridges

Biotage flash cartridges for purification are manufactured from polypropylene and polyethylene that meet or exceed the extractable requirements in US 21 CFR 177.1520 and are packed using proprietary methods that strictly adhere to ISO 9001:2000 quality standards. Cartridge sizes range from 2 g to 40 kg. Biotage cartridges undergo a stringent series of tests including shock resistance and chromatography testing for maximum quality. SNAP cartridges are laser-etched with a unique lot number to ensure traceability.

Biotage Flash purification

Flash purification is a technique developed by Professor W.C. Still that uses a column or cartridge filled with an insoluble solid support (stationary phase) and elution solvent mixture (mobile phase) to separate and purify a mixture of organic compounds. The stationary phase and the mobile phase typically have very different polarities, which work in tandem to separate compound mixtures. The separated molecules can then be collected in a purified state for use in a subsequent synthesis or as a final product. In 1994, Biotage was the first to develop and introduce pre-packed cartridges for flash purification. A broad selection of distinct cartridge styles now enable professionals to choose the cartridge which best suits the purification need and purification system:

• Biotage® SNAP 
• Biotage® SNAP Ultra
• Biotage® SNAP XL 
• Biotage Zip®
• Biotage Zip® Sphere
• Biotage® Flash 75
• Biotage® Flash 150
• Biotage® Flash 400

All Biotage cartridges are designed to meet the requirements of HPFC (high-performance flash chromatography) systems including Biotage Isolera™ Prime, Isolera™ One, Four and LS, Biotage SP1, Biotage SP4, and Biotage FlashMaster. Automated cartridge-packing techniques ensure efficiently packed Biotage flash cartridges minimize performance variability. Cartridge sizes range from 5 g to 40+ kg for purification scales ranging from milligrams to kilograms. Manufactured from polypropylene to meet the extractable requirements in US 21 CFR 177.1520 and packed using proprietary methods that strictly adhere to ISO 9001:2000 quality standards, Biotage cartridges also undergo QC testing and production control. Each Biotage SNAP cartridge is laser-etched with a unique lot number to ensure traceability.