Drug screening using oral fluid has gained popularity over recent years due to its simple, non-invasive collection means. Screening drugs of abuse can be complicated due to the wide variation of functional groups associated with different analyte classes. Most extraction techniques cannot extract all analytes using a single procedure without using non-optimal extraction protocols, resulting in compromised extract cleanliness. SLE allows for the simultaneous analysis of cross-functional analytes in a single extraction protocol without forfeiting extract cleanliness. This poster demonstrates the extraction of a range of drugs of abuse prior to UPLC-MS/MS analysis. The target analyte list includes benzodiazepines, z drugs, amphetamines, cathinones, opiates, cocaine, buprenorphine, PCP, THC-COOH, fentanyl and ketamine.
Extraction of Amphetamines and Analogues from Hair Using ISOLUTE® SLE+ Prior to GC/MS Analysis
Four Posters Presented at ASMS, Indianapolis
Video Tip: What is ISOLUTE® Filter+
Media Porosity, Why Should I Care?
Extraction of Polyfluorinated Compounds in Water Using EVOLUTE® EXPRESS WAX SPE Prior to LC-MS/MS Analysis