A new Application Note from Biotage was released today describing the extraction of Butalbarbital, Butabarbital, Amobarbital, Pentobarbital, Secobarbital, Hexobarbital and Phenobarbital from oral fluid matrix collected using the Oral-Eze® collection devices, prior to GC/MS analysis.
ISOLUTE® SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquidliquid extraction (LLE) for bio-analytical sample preparation, providing high analyte recoveries, no emulsion formation, and significantly reduced sample preparation.
This application note describes an effective and efficient ISOLUTE SLE+ protocol optimized for the 400 μL sample capacity column format. The simple sample preparation procedure delivers clean extracts and analyte recoveries greater than 95% with RSDs lower than 9% for all analytes.
White Paper: Reduce Solvent Use by 50%
Perfecting Your Mass Spectrometer Parameters
Sample Preparation Strategies for Urine Panels with 50 Drugs
Biotage Synthesizer Peer-reviewed Literature
How to Identify Compounds in a Mass Spectrum