The protocol described is optimized for the 1 mL capacity ISOLUTE SLE+ column format. The simple sample preparation procedure delivers clean extracts and analyte recoveries greater than 70% with RSDs lower than 10% for all analytes.
ISOLUTE® SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation, and significantly reduced sample preparation.
Download the application note below.
This concludes the Biotage Application Note series covering extraction of all the major drug classes from NeoSal oral fluid collection devices.
Biotage Awarded for Most Recognized Evaporator
Extraction of Thyroid Hormones: T3, rT3 and T4 from Serum Using EVOLUTE® EXPRESS AX Plates Prior to LC-MS/MS Analysis
Extraction of Vitamin B7 (Biotin) from Serum Using EVOLUTE® EXPRESS ABN
Biotage Wins Five-year Peptide Patent Dispute with CEM
Are You Looking to Analyze Acrylamide in Potato Chips or Coffee – Biotage Has the Answer