The protocol described is optimized for the 1 mL capacity ISOLUTE SLE+ column format. The simple sample preparation procedure delivers clean extracts and analyte recoveries greater than 70% with RSDs lower than 10% for all analytes.
ISOLUTE® SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation, and significantly reduced sample preparation.
Download the application note below.
This concludes the Biotage Application Note series covering extraction of all the major drug classes from NeoSal oral fluid collection devices.
White Paper: Reduce Solvent Use by 50%
Perfecting Your Mass Spectrometer Parameters
Sample Preparation Strategies for Urine Panels with 50 Drugs
Biotage Synthesizer Peer-reviewed Literature
How to Identify Compounds in a Mass Spectrum