Barbiturates are central nervous system depressants with sedatives properties in medicine. As with many other drugs they also also have recreational use with high addiction rates and risk of overdosing.
This application note describes an effective and efficient ISOLUTE SLE+ protocol optimized for 1 mL sample volumes. The simple sample preparation procedure delivers clean extracts and analyte recoveries greater than 88% with RSDs lower than 6% for all analytes.
ISOLUTE® SLE+ supported liquid extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation, and significantly reduced sample preparation.
Extraction of Thyroid Hormones: T3, rT3 and T4 from Serum Using EVOLUTE® EXPRESS AX Plates Prior to LC-MS/MS Analysis
Extraction of Vitamin B7 (Biotin) from Serum Using EVOLUTE® EXPRESS ABN
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