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Application Suite for Extraction of Methylmalonic Acid

02 February 2016

Five new application notes from Biotage labs provide a suite of methods for effective extraction of methylmalonic acid from serum using modern sample preparation techniques and materials from the ISOLUTE® and EVOLUTE ® product ranges. 

 

Methylmalonic acid (MMA) in serum is measured to help diagnose a number of disorders, primarily vitamin B12 deficiency. This suite of application notes describe the extraction of MMA from serum using a number of different extraction techniques (solid phase extraction, phospholipid depletion and supported liquid extraction). 

Structures of methylmalonic acid (MMA) and succinic acid (SA).

Structures of methylmalonic acid (MMA) and succinic acid (SA).