This application note describes the extraction of the immunosuppressant drug mycophenolic acid and its metabolite mycophenolic acid glucuronide from fortified serum using ISOLUTE® SLE+ in a 96-well plate format.
The ability to quantitate the amount of free drug and metabolite in patient serum is supported by using a fast and efficient supported liquid extraction sample preparation method using ISOLUTE® SLE+plates. The free drug and metabolite can be recovered from serum using ISOLUTE SLE+ with high enough efficiency to allow for quantitation at target trough levels.
Webinar Recording: Developing a Comprehensive Urine Pain Panel
How to Develop a Scalable Metals Removal Process in Chemistry
Extraction of Phosphatidylethanol Species from Whole Blood Using ISOLUTE® SLE+
Automated Fractionation of Extractable Petroleum Hydrocarbons (EPH) in Soil
Current Methodologies for Drugs of Abuse Urine Testing