This application note describes the extraction of the immunosuppressant drug mycophenolic acid and its metabolite mycophenolic acid glucuronide from fortified serum using ISOLUTE® SLE+ in a 96-well plate format.
The ability to quantitate the amount of free drug and metabolite in patient serum is supported by using a fast and efficient supported liquid extraction sample preparation method using ISOLUTE® SLE+plates. The free drug and metabolite can be recovered from serum using ISOLUTE SLE+ with high enough efficiency to allow for quantitation at target trough levels.
Biotage Goes Direct in Italy
New Peptide Synthesis Workflow Brochure
Extraction of Plasma Catecholamines and Metanephrines Using EVOLUTE® EXPRESS WCX SPE Prior to LC-MS/MS Analysis
New Second Generation Solvent Evaporators from Biotage
Extraction of Tobacco-Specific Nitrosamines (TSNAs) from Urine Using ISOLUTE® SLE+ Prior to UPLC/MS/MS Analysis