Part No: AN807Issued year: 2013File size: 1.05mbFile type: pdf
This application note describes an SPE protocol appropriate for LC-MS/MS analysis of aflatoxin M1 found in infant formula.
The method described in this application note achieves high recoveries of aflatoxin M1 from infant formula with %RSDs and LOQs that all meet the requirements set in European regulations for its measurement.
Part No: AN711Issued year: 2011File size: 0.11mbFile type: pdf
The following methods have been developed and optimized for the extraction of chloramphenicol from a variety of sample matrixes including milk, plasma, honey, urine, and shrimp/prawns for subsequent LC-MS/MS analysis. The methods are highly reproducible and offer low limits of detection.
AFFINILUTE, SupelMIP, MIP, Molecularly Imprinted Polymers,
Part No: AN714Issued year: 2011File size: 0.1mbFile type: pdf
The following methods have been developed and optimized for the extraction of fluoroquinolones (FQL) from a variety of sample matrixes including bovine kidney, honey, and milk. Example FQLs include sarafloxacin, norfloxacin, enrofloxacin, ciprofloxacin, lomefloxacin, and ofloxacin.
MIP, BIOTAGE, AFFINILUTE, SupelMIP, Molecularly Imprinted Polymers
Part No: AN732Issued year: 2011File size: 0.21mbFile type: pdf
This application note describes the extraction of melamine from biological fluids using EVOLUTE CX. Melamine's low cost and high nitrogen content has led to exploitation in various sections of the food industry, most notably involving dairy products.
Biotage, cation exchange, oasis, food scare, china,
Part No: AN749Issued year: 2011File size: 0.28mbFile type: pdf
Melamine is traditionally used in making plastics, however, it’s low cost and high nitrogen content has led to exploitation in various sections of the food industry, most notably involving dairy products. Sustained melamine exposure can result in kidney stones and renal failure, with the young being most susceptible. This application note has been optimized on the RapidTrace+; an updated version of the current RapidTrace software which allows the system to process smaller bed heights than were previously possible. The application note shows recoveries of 88-90% with RSDs <10%.
Melamine, food scare, china, EVOLUTE, cation exchange, RapidTrace, Automation, SPE, sample prep,
Part No: AN710Issued year: 2010File size: 0.1mbFile type: pdf
Molecularly imprinted polymers (MIPs) are a class of highly cross-linked polymers- engineered to bind one target compound or a class of structurally related target compounds with high selectivity. Selectivity is introduced during MIP synthesis in which a template molecule, designed to mimic the analyte, guides the formation of specific cavities or imprints that are sterically and chemically complementary to the target analyte(s). It is therefore critical for analysts to use the methodology described below when using this phase. Conventional generic methodologies employed with conventional SPE chemistries (e.g., reversed-phase C18) will yield sub-optimal results when employed with this phase.
SupelMIP, AFFINILUTE, Molecularly Imprinted Polymers, MIP
Part No: AN798Issued year: 2013File size: 1.33mbFile type: pdf
This application note describes a novel sample cleanup strategy to address the complex matrix effects associated
with commercial milk product variables while maintaining adequate analyte recovery and repeatability.
Part No: PPS318Issued year: 2013File size: 2.05mbFile type: pdf
ISOLUTE® Myco SPE columns offer simple and efficient multiple mycotoxin sample preparation from a wide range of matrices, ideally suited for selective and fast LC-MS/MS analysis. ISOLUTE Myco SPE columns contain a novel polymer-based sorbent designed specifically to be selective enough to isolate a wide variety of different mycotoxins. One product with multiple applications, simplifying and streamlining your mycotoxin analysis procedures.
Part No: Issued year: 2017File size: 0.31mbFile type: pdf
This poster includes a simple Load-Wash-Elute solid phase extraction method using EVOLUTE EXPRESS WCX, for extraction of aminoglycoside antibiotics from a range of meat, milk and egg samples.
The sample preparation method is automated using Biotage Extrahera, with fast, sensitive analysis utilizing HILIC-MS/MS with MRM Spectrum Mode for ID confirmation (Shimadzu LCMS-8060).