EPA Method 1657 describes the procedure to determine low ppb levels of organophosphorous pesticides in wastewater. The disks compared in this study are: “Certified for Automation” Atlantic™ C18 (47 mm) and 3M Empore™ High Performance Extraction Disk C18 (47 mm).

4790 Application Notes Azinphos methyl Chlorpyrifos Demeton (O&S) Diazinon Disk Disulfoton EPA 1657 analytes EPN English Environmental Ethion Ethyl parathion GC-FPD Malathion Methyl parathion Organophosphate Pesticide Waste water

Method 1657 describes the procedure to determine low ppb levels of organophosphorus pesticides in municipal and industrial wastewater. The City of Fort Worth Water Department implemented Automated SPE for the analysis of organophosphorous pesticides by EPA Method 1657, using the Atlantic™ C18 solid phase extraction disk. The Biotage® Horizon 4790 Automated Extraction System with Envision® Platform controller, and the DryVap® Automated Drying and Concentration System were used in this application note.

4790 Application Notes Azinphos methyl Chlorpyrifos Demeton (O&S) Diazinon Disk Disulfoton EPA 1657 analytes EPN English Environmental Ethion Ethyl parathion GC-FPD Malathion Methyl parathion Organophosphate Pesticide Waste water

This evaluation study was conducted to determine the feasibility of the Biotage SPE-DEXÒ 4790 Automated Extraction System for the extraction of herbicides and pesticides. The preliminary results demonstrate the capability of this method for the automated SPE extraction of organic compounds.

Acetochlor Alachlor Application Notes Atrazine Base-neutral herbicides Chlorothalonil Chlorpyrifos Clomazone Cyanazine Deethylatrazine, Demethanamid Desethyl atrazine Desisopropyl atrazine Diazinon Dimethoate Disk EPTC English Environmental Ethafluralin Fonofos GC-MS Malathion Metazachlor Methyl parathion Metolachlor Metribuzin Metribuzin DA Metribuzin DADK Metribuzin DK Pendimethalin Persistant organic pollutants (POP) Pesticides Phorate Prometon Propachlor Propazine Simazine Terbufos Triallate Trifluralin Water

In postmortem cases, where drugs or pesticides have been used for their poisonous properties, traditional matrices such as urine and whole blood may be inappropriate for qualitative and quantitative analysis. As the site of metabolism for most drugs and toxins, the liver may provide more insight to cause of death than other bodily fluids. This poster describes the use of ISOLUTE SLE+ supported liquid extraction columns to extract a range of drug and pesticide classes form homogenised liver using a simple, streamlined workflow. SOFT 2016

Alprazolam Amphetamine Atrazine Bead Ruptor Bendiocarb Biphenthrin Butabarbital Chlorothalonil Clinical Clonazepam Cocaine Column Diazepam Drugs of Abuse English Estazolam Forensic GC-MS Ketamine Liver MDMA Malathion Methadone Methamphetamine Midazolam Nitrazepam Pesticides Phenobarbital Posters Propanil Secobarbital THC Triazolam

This application note describes the extraction of a broad range of analytes from liver tissue matrix prior to GC/MS analysis using ISOLUTE® SLE+ supported liquid extraction columns. A protocol has been developed that allows the simultaneous extraction of various drugs of abuse classes: amphetamines, barbiturates, benzodiazepines, cocaine, ketamine, THC. In addition to these drug panels, simultaneous extraction of carbamate, organochlorine, organophosphate, pyrethroid, and triazine pesticide classes is demonstrated.

Alprazolam Amphetamine Application Notes Atrazine Bead Ruptor Bendiocarb Biphenthrin Butabarbital Chlorothalonil Clinical Clonazepam Cocaine Cocaines Column Diazepam Drugs of Abuse English Estazolam Forensic GC-MS Ketamine Liver MDMA Malathion Methadone Methamphetamine Midazolam Nitrazepam Pesticides Phenobarbital Propanil Secobarbital THC Triazolam

This poster describes a simple but effective method for screening a range of pesticides and drugs of abuse from liver samples. Liver tissue is homogenized using the Biotage® Lysera, and the subsequent extract is cleaned up using ISOLUTE SLE+ supported liquid extraction columns. ASMS 2017

Alprazolam Amphetamine Amphetamines Atrazine Barbiturates Bead Ruptor Bendiocarb Benzodiazepines Biphenthrin Butabarbital Chlorothalonil Clinical Clonazepam Cocaine Cocaines Column Diazepam Drugs of Abuse English Estazolam Forensic GC-MS Ketamine Liver MDMA Malathion Methadone Methamphetamine Midazolam Nitrazepam Organochlorine pesticides (OCP) Pesticides Phenobarbital Posters Propanil Secobarbital THC Triazolam