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Acid herbicides Acidic Alcohol metabolite Aliphatic hydrocarbons Aminoglycoside antibiotics Amphetamines Anabolic steroids Anaesthetic Analgesics Antibiotics Anticoagulant Anticonvulsant Antiepileptics Antimicrobial Aromatic hydrocarbons B Vitamins Barbiturates Base-neutral herbicides Basic Benzodiazepines Beta blockers Biomarker Brominated Flame Retardants (BFRs) Bronchodilator Cannabinoid Carbamate hypnotic Carbamate muscle relaxant Carbamates Catecholamines Cathinones Cocaines Corrosion inhibitors Corticosteroids Designer stimulants Diarrhetic Shellfish Poisoning (DSP) Toxins Diuretics Dried chili Drugs of Abuse Environmental contaminants Estrogens Fat Soluble Vitamins Fluoroquinolones Food contaminant Hallucinogen Hexane Extractable Material Imidazoline corrosion inhibitor Imidazolines Immunosuppressant Legal highs Lipids Marine Toxins Metanephrines Mycotoxin NBOMes NSAIDs Neutral Nicotine metabolites Nitroimidazoles Opiates Opioid Opioid agonist Organochlorine pesticides (OCP) Organophosphate Pesticide Over the counter pharmaceuticals PAHs PBDEs PCBs Pain Management Paralytic Shellfish Poisoning (PSP) Toxins Peptides Persistant organic pollutants (POP) Pesticides Pharmaceuticals Phenethylamines Phenols Phthalate Metabolites Phthalates Phthalic acid esters Plasticisers Polyaromatic Hydrocarbons (PAH) Polyfluorinated acids Preservative Quaternary Amines SERM (selective estrogen receptor modulator) Spice Steroid Hormones Steroid metabolite Stimulants Sympathomimetic amine Synthetic Cannabinoids (SPICE) THC metabolites Thyroid Hormone Tobacco Specific Nitrosamines (TSNAs) Triazine Herbicides Triazines Tricyclic Antidepressant Triphenylmethane Dyes Vitamin D Vitamins Water Soluble Vitamins z-drugs β-agonists β-blockers

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2 results

Sort by: Title Document number Year File type File size

A Novel Drug Screening Protocol for Acidic, Basic, and Neutral Drugs in Hydrolyzed Urine using Supported Liquid Extraction prior to LC-MS/MS Analysis

Part No: P144 Issued year: 2016 File size: 0.6mb File type: pdf

The ability to extract a broad range of different drugs from a biological matrix allows for the expedited analysis of a patient sample using LC-MS/MS. Typically small molecules are extracted from matrices like urine based on their polarities. A fast and reliable sample preparation method that could be implemented to extract drugs of different polarities from urine could be used as a screening tool to quickly identify the presence of illicit drugs in patient samples using LC-MS-MS. This poster demonstrates the utility of supported liquid extraction for the extraction of over 30 different acidic, basic and neutral drugs in urine prior to LC-MS/MS. MSACL 2016

11-hydroxy- Δ9-tetrahydrocannabinol (THC-OH) 11-nor- Δ9-carboxy tetrahydrocannabinol (THC-COOH) 6-acetyl codeine 96-well plate Acidic Alprazolam Amphetamine Barbiturates Basic Benzodiazepines Benzoylecgonine Buprenorphine Butalbital Clinical Clonazepam Codeine Dextromethorphan Diazepam Drugs of Abuse EDDP English Fentanyl Flunitrazepam Forensic Hydrocodone Hydrolysed urine Hydromorphone LC-MS/MS MDEA Morphine Naltrexone Neutral Nitrazepam Norbuprenorphine Norcodeine Norfentanyl Opiates Oxazepam Oxycodone Oxymorphone Pain Management Pentazocine Pentobarbital Phenobarbital Posters Propoxyphene Secobarbital THC THC metabolites THC-COOH Temazepam Δ9-tetrahydrocannabinol (THC)

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Acidic, Basic, and Neutral Drug Screen of Hydrolyzed Urine Using Supported Liquid Extraction Prior to LC-MS/MS Analysis

Part No: AN859 Issued year: 2016 File size: 0.93mb File type: pdf

This application note describes the extraction of acidic, basic, and neutral drugs from urine for screening purposes using ISOLUTE® SLE+ supported liquid extraction plates prior to LC-MS/MS analysis.

11-hydroxy- Δ9-tetrahydrocannabinol (THC-OH) 11-nor- Δ9-carboxy tetrahydrocannabinol (THC-COOH) 6-acetyl codeine 96-well plate Acidic Alprazolam Amphetamine Application Notes Barbiturates Basic Benzodiazepines Benzoylecgonine Buprenorphine Butalbital Clinical Clonazepam Codeine Dextromethorphan Diazepam Drugs of Abuse EDDP English Fentanyl Flunitrazepam Forensic Hydrocodone Hydrolysed urine Hydromorphone LC-MS/MS MDEA Naltrexone Neutral Nitrazepam Norbuprenorphine Norcodeine Norfentanyl Normeperidine Opiates Oxazepam Oxycodone Oxymorphone Pain Management Pentazocine Pentobarbital Phenobarbital Propoxyphene Secobarbital THC metabolites Temazepam Urine Δ9-tetrahydrocannabinol (THC)

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