Extraction of NSAIDs from Various Matrices Using AFFINILUTE™ MIP – NSAIDs
Part No: AN705
Issued year: 2010
File size: 0.1mb
File type: pdf
Molecularly imprinted polymers (MIPs) are a class of highly cross-linked polymers- engineered to bind one target compound or a class of structurally related target compounds with high selectivity. Selectivity is introduced during MIP synthesis in which a template molecule, designed to mimic the analyte, guides the formation of specific cavities or imprints that are sterically and chemically complementary to the target analyte(s). It is therefore critical for analysts to use the methodology described below when using this phase. Conventional generic methodologies employed with conventional SPE chemistries (e.g., reversed-phase C18) will yield sub-optimal results when employed with this phase.
molecularly imprinted polymers, MIP, BIOTAGE, AFFINILUTE, NSAIDs, Environmental, SupelMIP
Application Notes
Clinical
Clofibric Acid
Column
Ibuprofen
LC-MS/MS
NSAIDs
Naproxen
Post-Mortem fluids
Post-Mortem tissue
Water