Part No: Issued year: 2006File size: 0.83mbFile type: pdf
• Novo Nordisk A/S & radiochemistry at Novo Nordisk A/S
• Introduction to radiochemistry in general
• Radiochemistry & microwaves
• Selected case stories from the labs at Novo Nordisk A/S
• Applications of radiolabelled compounds
• Summary and acknowledgements
Part No: P016Issued year: 2007File size: 0.16mbFile type: pdf
In order to obtain a fast synthesis of an N-unprotected tripeptide, microwave (mw) assisted deprotection, coupling and partial deprotection were applied starting with a purified protected dipeptide [Fig. 1]. The three consecutive mw assisted steps were performed without any intermediate purifications and were accomplished within some 30 minutes. The resulting crude mixture containing the Boc deprotected tripeptide ester was shown to be quite complex [Fig. 2]. The crude product was subjected to automated reversed phase flash chromatography, followed by automated fraction pooling and “thin film evaporation”. The total time for the entire procedure was 1 h 20 min. The purity of the product was > 99%.
Part No: PPS433Issued year: 2016File size: 0.78mbFile type: pdf
Customer Case: Japan Frozen Foods Inspection Corporation.
The Japan Frozen Foods Inspection Corporation (JFFIC) made the transition from traditional mouse
testing of shellfish toxins, to instrumental analysis by developing original methods. In the sample
preparation procedure JFFIC uses EVOLUTE® ABN hydrophilic/hydrophobic SPE columns from Biotage.
Part No: PPS426Issued year: 2016File size: 0.38mbFile type: pdf
Customer case: Welsh Water. Analytical on-line cartridges for environmental testing from Biotage were released in 2016. Russell Gibbs from Dŵr Cymru Welsh Water has just started using them for drinking water testing.
Part No: CM-TRIT-0810Issued year: 2010File size: 0.26mbFile type: pdf
Trityl-ChemMatrix is mainly used to obtain a protected peptide as is has very low TFA cleavage conditions (under 1%). This resin therefore has the same cleavage conditions as the Cl-Trityl-polystyrene. On request, Trityl-ChemMatrix resins can
be offered preloaded will all 20 natural amino acids. Other amino acids can be preloaded on special request. Please take note that the Cl-Trityl-ChemMatrix resin is not offered for stability reasons. It is most effective to start with the Trityl-
OH-ChemMatrix resinchlorinate the resin and then add the amino acid of desire.
Part No: PPS448Issued year: 2017File size: 0.83mbFile type: pdf
The TurboVap® 96 is a high speed concentrator designed to work with 96-well microplates and deep-well plates. It is an efficient alternative to the constant monitoring and long evaporation times that are characteristic of conventional techniques — with the added bonus of unattended operation.